COMPARISON OF DOBUTAMINE AND REGADENOSON STRESS CMR

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项建议旨在确定与多巴酚丁胺负荷室壁运动检查结果相比，使用瑞格腺苷(来克西康)实施磁共振心血管负荷灌注检查的可行性、工作人员的努力、患者的舒适度和假阳性率。该项目将招募计划接受多巴酚丁胺负荷核磁共振检查的有反应性呼吸道疾病(慢性阻塞性呼吸道疾病或哮喘)的患者。在我们机构，这代表着20%？25%的患者被转介进行压力测试，或者说每天1到2例。将根据IRB和HIPPA监管协议批准的指导方针联系所有潜在的候选人。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This proposal is designed to determine the feasibility, staff effort, patient comfort, and false positive rate of implementing a MRI cardiovascular stress perfusion exam with regadenoson (Lexiscan¿?¿) relative to the results obtained during a MRI dobutamine stress wall motion exam. This project will enroll individuals that are scheduled for a dobutamine stress MRI with reactive airways disease (chronic obstructive airway disease or asthma). At our institution this represents 20 ¿?? 25% of patients that are referred for stress testing, or 1 to 2 cases per day. All potential candidates will be contacted in accordance with guidelines approved by the IRB and HIPPA regulatory accords.