TREATMENT OF SENTENCE PROCESSING DISORDERS IN APHASIA

PI和Co-PI一直是主要的研究机构 contributors-隐含一个语法到语义的映射赤字作为核心 不流利、布罗卡氏失语症的语法紊乱特征。 因此，我们的神经语言学家和语言病理学家团队 已经寻求开发针对映射操作的治疗方案， 沿着直接与映射相关的动词检索操作。 我们 初步的成功加强了这样一种信念，即治疗的动机是 神经语言学的发现和针对组件缺陷有一个 在失语症患者的临床管理中发挥重要作用。 经过适当设计和充分测试，此类治疗可包括 模块化的建筑块的方案，为恢复复杂的 语言技能，如口头表达。 这个“模块化治疗”主题 在这三部分提案中，按照以下内容进行了详细阐述 具体目标： 第一部分：比较语法缺失症的两种治疗方法--句法 刺激和映射疗法-针对不同神经语言 操作;并检查有序组合的功效， 两个疗程。 第二部分：继续发展动词处理方案， 同时鼓励词汇语义，句法和语音 动词在句子语境中的加工;操纵“深度” 动词意义的“加工”是这种加工的一个自变量; 第III部分：促进治疗效果的延续， 功能结果，通过逐步泛化训练 一个模块，旨在弥合约束和自然之间的差距 口头生产任务;

A body of research-to which the PI and Co-PI have been major contributors-implicates a syntax-to-semantics mapping deficit as a core feature in the grammatical disorder of nonfluent, Broca's aphasics. Consequently, our team of neurolinguists and speech-language pathologists has sought to develop treatment protocols that target mapping operations, along with verb retrieval operations that bear directly on mapping. Our preliminary successes reinforce the belief that treatments motivated by neurolinguistic findings and directed at components deficits have an important role to play in the clinical management of aphasic patients. Properly designed and adequately tested, such treatments may comprise the modular building blocks of programs for the rehabilitation of complex linguistic skills like oral production. This 'modular treatments' theme is elaborated in this 3-part proposal in accordance with the following specific aims: Part I: To compare the efficacy of two treatments for agrammatism-syntax stimulation and mapping therapy-which target different neurolinguistic operations; and to examine the efficacy of ordered combinations of the two treatments. Part II: To continue the development of a verb treatment program which simultaneously encourages lexico-semantic, syntactic, and phonological processing of verbs in sentence contexts; to manipulate 'depth of processing' of verb meaning as an independent variable in such treatment; Part IIl: To promote carry-over of treatment effects, and hence more functional outcomes, by means of a step-wise generalization training module aimed at bridging the gap between constrained and naturalistic oral production tasks;