Volumetric imaging facility: observing the cell in its native environment

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This project aims to establish a National volumetric imaging platform for functional imaging of multi-cellular networks. The facility will integrate new super-resolution imaging modalities, a library of near infrared molecular probes, and microfluidics technologies to enable real-time observation of 3D engineered organoids. This new optical imaging platform will allow users to watch the inner workings of cells through deep tissue with high speed, ultra-sensitivity, and in four dimensions, rather than today's typical two dimensions. Focus areas include the emerging development and study of mini versions of organs and hard-to-culture microbial matter. This facility is expected to provide benefits across the fields of physics, optics, chemical and material sciences, photonics, biotechnology and engineering.