A broad multi-program approach to rapidly identify and develop novel therapeutics and diagnostics for Covid-19 using Bicyclic Peptides (Bicycles)

一种广泛的多程序方法，可使用双环肽（Bicycles）快速识别和开发针对 Covid-19 的新型疗法和诊断方法

• 批准号: 73786
• 金额: $ 271.1万
• 依托单位: BICYCLE TX LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=73786
• 关键词: broad; multi; program; approach; rapidly

Bicycles are a new class of drug that can rapidly be identified using our unique platform technology and have utility if they can be developed as novel anti-virals for use in tackling the current and/or future covid pandemics. They also have potential as novel anti-inflammatory therapies tailored to the requirements of later stage Covid-19 disease sufferers that go on to develop severe inflammatory conditions in the hospital setting. In this application we propose a multi-target strategy to identify novel therapies to treat the ongoing, and potentially future, pandemics.

自行车是一种新的药物类别，可以使用我们独特的平台技术快速识别，如果它们能够被开发为新型抗病毒药物，用于应对当前和/或未来的Covid流行病，则具有实用价值。它们还具有作为新型抗炎疗法的潜力，这些疗法是为新冠肺炎晚期患者的要求量身定做的，这些患者在医院环境中继续发展为严重的炎症条件。在这项申请中，我们提出了一种多靶点战略，以确定治疗正在进行的以及潜在的未来大流行的新疗法。