MICROCOIL BASED PROBES FOR NANOLITER VOLUME NMR

这项研究和开发工作的总体目标是 一系列专门的显微镜探针的商业化， 核磁共振（NMR）光谱。可行性研究将 进行，包括建模，设计，施工， 基于微线圈的探针的实验测试， 5 nl至100 nl，每种都具有皮摩尔灵敏度。主要目的是 实现实现高分辨率所需的光谱分辨率 分辨率NMR技术。有了这些微探针，NMR将被添加到 适用于纳升体积的分析技术列表， 纳克质量样品。微探针有望提供前所未有的 灵敏度

The overall goal of this research and development effort is the commercialization of a family of specialized microscopic probes for nuclear magnetic resonance (NMR) spectroscopy. A feasibility study will be conducted that includes the modeling, design, construction, and experimental testing of microcoil-based probes with volumes ranging from 5 nl to 100 nl, each with picomole sensitivity. The major aim is to achieve the spectral resolution necessary for implementation of high resolution NMR techniques. With these microprobes, NMR will be added to the list of analytical techniques appropriate for nanoliter volume, nanogram mass samples. The microprobes promise to provide unprecedented sensitivity.