YEAST PROTEOME DATABASE--INTERFACE OF 2D GELS TO YPD

酵母蛋白质组数据库--2D 凝胶与 YPD 的接口

• 批准号: 2660606
• 负责人: JAMES I GARRELS
• 金额: $ 9.46万
• 依托单位: PROTEOME, INC.
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-01 至 1998-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2660606
• 关键词: Internet; Saccharomyces cerevisiae; computer program /software; computer system design /evaluation; gel electrophoresis; information systems; protein sequence; protein structure; technology /technique development; yeasts

DESCRIPTION: (adapted from applicant's abstract) This project seeks to build a new bioinformatics analysis platform through connection of an established protein analysis technique (2D gel electrophoresis) with a proteome database (YPD™) already successfully developed and commercialized by Proteome, Inc. The yeast Protein Database (YPD™) is a ongoing project that extract information on yeast proteins from the literature through a rigorous process of curation and editing, and this data is currently distributed to thousands of academic scientists and dozens of commercial subscribers through the Internet and commercial Intranets. Two-dimensional gel electrophoresis has become a technique of renewed importance for functional genome analysis, a field sometimes called proteomics. Proteome, Inc., seeks to build a data system that is a practical interface for proteome research by linking YPD™ with their emerging two-dimensional gel database for the yeast, Saccharomyces cerevisiae. This expanded resource will contain information on expression levels, experimental data on protein modifications, protein complex information, etc. for thousands of the proteins that can be resolved and identified from the yeast proteome. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

描述：（改编自申请人的摘要）本项目旨在 通过连接一个生物信息学分析平台， 已建立的蛋白质分析技术（2D凝胶电泳）， 蛋白质组数据库（YPD）已经成功开发， 由Proteome，Inc.酵母蛋白质数据库（YPD） 是一个正在进行的项目，从酵母蛋白质中提取信息， 文学通过严格的策展和编辑过程，这 数据目前分发给数千名学术科学家， 数十个商业用户通过互联网和商业 内部网。双向凝胶电泳已经成为一种技术 功能性基因组分析的重要性，一个领域有时 叫做蛋白质组学。 Proteome，Inc.，试图建立一个数据系统， 是一个实用的蛋白质组研究接口，™ 随着他们新兴的酵母二维凝胶数据库， 酿酒酵母 这个扩展的资源将包含 表达水平信息、蛋白质实验数据 修饰，蛋白质复合物信息等，为成千上万的 可以从酵母蛋白质组中解析和鉴定的蛋白质。 拟议商业应用：不可用