Unifying mechanisms of innate immunity signaling in animals and plants
Unifying mechanisms of innate immunity signaling in animals and plants
批准号:
FL180100109
负责人:
Prof Bostjan Kobe
金额:
$195.52万
依托单位国家:
澳大利亚
项目类别:
Australian Laureate Fellowships
财政年份:
2019
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2019-01-01 至 2023-12-31
中文摘要
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英文摘要
This project aims to improve our understanding of innate immunity, the first line of defense against pathogens in diverse organisms. Innate immune pathways are key to a range of pathological states in animals, and provide plants with resistance to the diseases that account for 15% of crop losses. This project will generate knowledge, through characterising mechanisms of cell signalling for mammalian and plant innate immunity. The outcomes will include a unified signalling model, and form the foundation for a range of applications in human biology and agriculture, such as the development of durable and effective resistance in crops.
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Nanocrystal Electron Diffraction Facility
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财政年份:2019
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依托单位:
Automated high resolution and high contrast cryo -TEM for three-dimensional structural biology
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批准号:LE180100179
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$212.64万
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财政年份:2018
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负责人:Prof Bostjan Kobe
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依托单位:
Structural biology and therapeutic targeting of proteins involved in infection and immunity
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批准号:nhmrc : GNT1110971
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项目类别:Research Fellowships
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资助金额:$75.33万
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财政年份:2016
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负责人:Prof Bostjan Kobe
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依托单位:
Structural biology and therapeutic targeting of proteins involved in infection and immunity
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批准号:nhmrc : 1110971
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项目类别:Research Fellowships
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财政年份:2016
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负责人:Prof Bostjan Kobe
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Molecular mechanism of action of plant immune receptors
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财政年份:2016
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依托单位:
Protein glycan interactions in infectious diseases.
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批准号:nhmrc : GNT1071659
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资助金额:$879.58万
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财政年份:2015
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负责人:Prof Bostjan Kobe
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依托单位:
Protein glycan interactions in infectious diseases.
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批准号:nhmrc : 1071659
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项目类别:Program Grants
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资助金额:$612.27万
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负责人:Prof Bostjan Kobe
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Understanding the molecular function of plant disease resistance proteins, pathogen effectors and their interaction to protect Australian agriculture
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财政年份:2012
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负责人:Prof Bostjan Kobe
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依托单位:
Structural biology of infection and immunity
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批准号:nhmrc : 1003325
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项目类别:Research Fellowships
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资助金额:$44.31万
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财政年份:2011
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依托单位:
Molecular basis of the interaction between plant disease resistance proteins and pathogen avirulence proteins
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批准号:DP0984827
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财政年份:2009
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依托单位:
Functional and structural characterisation of Defective embryo and meristems (Dem) proteins involved in plant development.
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批准号:DP0559710
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项目类别:Discovery Projects
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资助金额:$18.02万
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财政年份:2005
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依托单位:
New approaches to functional and structural genomics
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批准号:FF0561371
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项目类别:Federation Fellowships
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资助金额:$108.92万
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财政年份:2005
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负责人:Prof Bostjan Kobe
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依托单位:
Structural biology
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批准号:nhmrc : 252736
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项目类别:NHMRC Research Fellowships
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资助金额:$30.21万
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财政年份:2003
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负责人:Prof Bostjan Kobe
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依托单位:
Molecular basis of dengue virus-induced fusion
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批准号:nhmrc : 252739
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项目类别:NHMRC Project Grants
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资助金额:$27.36万
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财政年份:2003
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负责人:Prof Bostjan Kobe
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依托单位:
Structural studies of plant disease resistance proteins
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批准号:DP0208353
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项目类别:Discovery Projects
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资助金额:$22.21万
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财政年份:2002
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负责人:Prof Bostjan Kobe
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依托单位:
Structural characterisation of phosphopeptide recognition by FHA domains
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批准号:nhmrc : 143013
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项目类别:NHMRC Project Grants
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资助金额:$17.14万
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财政年份:2001
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负责人:Prof Bostjan Kobe
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依托单位:
Structural characterisation of nuclear localisation signal-receptor recognition
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批准号:nhmrc : 991554
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项目类别:NHMRC Project Grants
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资助金额:$13.37万
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财政年份:1999
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负责人:Prof Bostjan Kobe
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依托单位:
国内基金
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