MODIFIABLE RISK FACTORS IN BLACKS WITH SLE

这一修订后的补助金是应以下项目的建议书提交的： 对美国少数民族的临床和流行病学研究。 并研究了社会、营养和环境因素对 低收入美国黑人和白人中的疾病活动， 红斑狼疮（SLE）。 几乎所有研究SLE流行病学的研究都观察到较高的 黑人患者的发病率和死亡率。较低的社会经济地位是 可以部分解释这种差异社会经济地位较低 与一些因素有关，如减少获得医疗保健， 疾病知识不足，社会支持不足， 等其中许多都符合公共卫生和社会政策 改善高危人群健康状况的战略。 建议进行多中心横断面研究。研究将证实 先前关于黑人患者发病率差异的观察结果， 确定具有公共卫生重要性的潜在可改变因素， 影响疾病活动。

This revised grant is submitted in response to a request for proposals on clinical and epidemiologic research on minority populations of the U.S. and studies the effect of social, nutritional and environmental factors on disease activity among low-income American Blacks and Whites with Systemic Lupus Erythematosus (SLE). Nearly all studies examining the epidemiology of SLE have observed higher morbidity and mortality for black patients. Lower socioeconomic status is believed to explain this discrepancy, in part. Lower socioeconomic status is associated with factors such as diminished access to health care, inadequate knowledge of disease, less availability of social supports, etc. Many of these are amenable to public health and social policy strategies to improve health status in high-risk populations. A multicentered cross-sectional study is proposed. The study will confirm previous observations on the discrepant morbidity of black patients and identify potentially modifiable factors of public health importance which affect disease activity.