Conference--Standards for Treatment of SLE Patients

描述（摘自申请人的摘要）：努力的目标 在这个补助金申请中提出的是进行一个共识会议， 国际临床科学家和临床试验方法学家小组 制定系统性红斑狼疮的标准化反应标准 (SLE)在现有疾病活动性衡量标准的“单位”中进行试验， 选择主要器官系统。SLE的实验治疗领域是 在一个陡峭的斜坡上发现和他们的评估在人类受试者将是 如果使用标准端点，则增强。标准反应标准将允许 试验之间有意义的比较，促进创新研究的使用 设计，并大大提高了效率，缩短了时间线， 测试新的干预措施。这笔赠款将支持利益攸关方会议， 根据国际数据制定共识反应标准 评估了1000多名患者的病史。 共识构建技术，如德尔菲和名义组技术， 被利用

DESCRIPTION (Taken from the applicant's abstract): The goal of the efforts proposed in this grant application is to conduct a consensus meeting of an international group of clinician-scientists and clinical trials methodologists to produce standardized response criteria for systemic lupus erythematosus (SLE) trials in the "units" of existing disease activity measures and by selected major organ systems. The field of experimental therapeutics in SLE is on a steep slope of discovery and their evaluation in human subjects will be enhanced if standard end points are used. Standard response criteria will allow meaningful comparisons between trials, promote the use of innovative study designs, and greatly improve the efficiency and shorten the time-line for testing new interventions. This grant will support a meeting of stakeholders to develop consensus response criteria based on data from an international pre-meeting exercise in which over 1000 patient histories were evaluated. Consensus building techniques, such as Delphi and nominal group techniques will be used.