US-A transatlantic partnership to identify novel factors that influence the development and function of M cells in the gut epithelium

美国-跨大西洋合作伙伴关系，以确定影响肠道上皮 M 细胞发育和功能的新因素

• 批准号: BB/K021257/1
• 负责人: Neil Mabbott
• 金额: $ 4.71万
• 依托单位: University of Edinburgh
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FK021257%2F1
• 关键词: US; transatlantic; partnership; identify; novel

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium.

• DOI: 10.1038/mi.2013.30
• 发表时间: 2013-07
• 期刊: Mucosal immunology
• 影响因子: 8

The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche.

• DOI: 10.1038/s41467-018-03638-6
• 发表时间: 2018-03-28
• 期刊: Nature communications
• 影响因子: 16.6
• 作者: Sehgal A;Donaldson DS;Pridans C;Sauter KA;Hume DA;Mabbott NA
• 通讯作者: Mabbott NA

An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells.

内源性纳米矿物伴侣将管腔抗原和肽聚糖与肠道免疫细胞结合。

• DOI: 10.1038/nnano.2015.19
• 发表时间: 2015-04
• 期刊: Nature nanotechnology
• 影响因子: 38.3

c-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epithelium.

• DOI: 10.1016/j.imbio.2016.09.008
• 发表时间: 2017-02
• 期刊: IMMUNOBIOLOGY
• 影响因子: 2.8
• 作者: Sehgal, Anuj;Kobayashi, Atsushi;Donaldson, David S.;Mabbott, Neil A.
• 通讯作者: Mabbott, Neil A.

Microbial Stimulation Reverses the Age-Related Decline in M Cells in Aged Mice

微生物刺激可逆转老年小鼠 M 细胞与年龄相关的下降

• DOI: 10.1101/2020.02.17.943514
• 发表时间: 2020
• 作者: Donaldson D