13TSB_N4L2FS: Development of silage inoculants to improve mineral composition of animal products

13TSB_N4L2FS:开发青贮饲料接种剂以改善动物产品的矿物质成分

基本信息

  • 批准号:
    BB/L021285/1
  • 负责人:
  • 金额:
    $ 3.51万
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Research Grant
  • 财政年份:
    2014
  • 资助国家:
    英国
  • 起止时间:
    2014 至 无数据
  • 项目状态:
    已结题

项目摘要

Consumers have an increasing fascination with the food they eat with a subsequent increase in demand for healthier, more nutritional functional food. This project will develop novel animal products which will increase the supply of bioavailable nutrients to the consumer reducing the reliance on dietary supplements. Se is essential for humans as a constituent of more than two dozen seleno-proteins which play critical roles in reproduction, thyroid hormone metabolism, DNA synthesis and protection from oxidative damage. Inadequate intakes of bioavailable Se are common in people living in Se-deficient regions, vegetarians and vegans. Se deficiency is also seen in patients' under-going kidney dialysis, people living with HIV and the elderly due to removal of Se through dialysis, increased loss through diarrhoea and malabsorption. Se is available in multimineral supplements as inorganic sodium selenate or sodium selenite. However, the human body absorbs only 50 % of Se as either selenate or selenite compared to over 90 % of Se in the form of organic selenomethionine and selenocysteine (IFMNB, 2000). Good sources of organic Se in the human diet are from animal products such as dairy and ruminant meat. However variability in composition is large due to the nature of the Se status of the soil during grazing and also the low levels of minerals contained typically in ensiled forage. A 2005 report estimated that typical UK silage contained less than 21 % of the Se requirement for optimum livestock nutrition (FWL, 2005). It is therefore common to supplement ruminants with minerals in the form of inorganic Se. As with humans the bioavailability of the inorganic form is significantly less than organic Se requiring a higher dose. In addition the conversion of inorganic Se into milk and muscle seleno-protein is inefficient resulting in lower levels in animal products for human consumption. Therefore the ability to use a silage inoculant which incorporates Se as an organic form will naturally increase the supply of available Se to animals and enrich products with a highly bioavailable form of the nutrient. As such the project will develop a novel method of nutrient delivery by enhancing organic Se in animal products. It will also develop a novel healthier food which will allow greater absorption of organic Se without the need for dietary supplementation through inorganic mineral tablets. In addition an increase in Se in animal products through greater antioxidant capacity will improve product shelf life and reduce waste.
消费者对他们吃的食物越来越着迷,随之而来的是对更健康、更有营养的功能食品的需求增加。该项目将开发新的动物产品,以增加对消费者的生物可利用营养素的供应,减少对膳食补充剂的依赖。硒是人体必需的二十多种硒蛋白的组成部分,这些硒蛋白在生殖、甲状腺激素代谢、DNA合成和保护免受氧化损伤等方面发挥着关键作用。生物可利用硒的摄入量不足在生活在缺硒地区的人、素食主义者和纯素食主义者中很常见。硒缺乏也见于正在进行肾脏透析的患者、艾滋病毒携带者和老年人,因为通过透析去除了硒,腹泻和吸收不良增加了损失。硒在多种矿物质补充剂中以无机亚硒酸钠或亚硒酸钠的形式存在。然而,人体只吸收50%的硒以亚硒酸盐或亚硒酸盐的形式存在,相比之下,超过90%的硒以有机硒蛋氨酸和硒半胱氨酸的形式存在(IFMNB,2000)。人类饮食中有机硒的良好来源是来自动物产品,如乳制品和反刍动物肉类。然而,由于放牧期间土壤硒状况的性质以及青贮饲料中典型的低水平矿物质含量,成分的变异性很大。2005年的一份报告估计,典型的英国青贮饲料中的硒含量不到最佳牲畜营养所需硒的21%(FWL,2005)。因此,用无机硒形式的矿物质来补充反刍动物是很常见的。与人类一样,无机形式的生物利用度明显低于有机硒,需要更高的剂量。此外,将无机硒转化为牛奶和肌肉硒蛋白的效率很低,导致供人类食用的动物产品中的硒含量较低。因此,能够使用将硒作为有机形式加入的青贮料接种剂,自然会增加动物有效硒的供应,并使产品富含高度生物可利用的营养物质。因此,该项目将通过提高动物产品中的有机硒来开发一种新的营养输送方法。它还将开发一种新的更健康的食品,这种食品将允许更多地吸收有机硒,而不需要通过无机矿物质片剂进行饮食补充。此外,通过更强的抗氧化能力增加动物产品中的硒将延长产品的保质期,减少浪费。

项目成果

期刊论文数量(10)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
The effect of selenium enriched silage on the selenium status of finishing lambs and their products.
富硒青贮饲料对育肥羔羊及其产品硒状况的影响
  • DOI:
  • 发表时间:
    2016
  • 期刊:
  • 影响因子:
    0
  • 作者:
    LEE M.R.F.
  • 通讯作者:
    LEE M.R.F.
Enrichment of lactic acid silage bacteria with Selenium by growing cultures in modified MRS broth supplemented with sodium selenite
通过在添加亚硒酸钠的改良 MRS 肉汤中培养培养物来富集乳酸青贮菌
  • DOI:
  • 发表时间:
    2015
  • 期刊:
  • 影响因子:
    0
  • 作者:
    FLEMING H. R.
  • 通讯作者:
    FLEMING H. R.
Selenium speciation in ruminant feed using liquid chromatography hydride generation atomic fluorescence spectrometry (HPLC-HG-AFS).
使用液相色谱氢化物发生原子荧光光谱法 (HPLC-HG-AFS) 分析反刍动物饲料中的硒形态。
  • DOI:
  • 发表时间:
    2014
  • 期刊:
  • 影响因子:
    0
  • 作者:
    LEE M.R.F.
  • 通讯作者:
    LEE M.R.F.
Key traits for ruminant livestock across diverse production systems in the context of climate change: perspectives from a global platform of research farms
  • DOI:
    10.1071/rd20205
  • 发表时间:
    2021-01-01
  • 期刊:
  • 影响因子:
    1.9
  • 作者:
    Rivero, M. Jordana;Lopez-Villalobos, Nicolas;Lee, Michael R. F.
  • 通讯作者:
    Lee, Michael R. F.
The effect of supra-optimal inorganic, organic and nano selenium on blood selenium status of ewes
超优无机硒、有机硒和纳米硒对母羊血硒状况的影响
  • DOI:
  • 发表时间:
    2017
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Lee M R F
  • 通讯作者:
    Lee M R F
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Michael Lee其他文献

Sustainable Composite Beam Behaviour with Deconstructable Bolted Shear Connectors
具有可解构螺栓剪力连接器的可持续复合梁行为
  • DOI:
  • 发表时间:
    2016
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Michael Lee;M. Bradford
  • 通讯作者:
    M. Bradford
A bifunctional Δ6‐fatty acyl acetylenase/desaturase from the moss Ceratodon purpureus
来自苔藓 Ceratodon purpureus 的双功能 Δ6-脂肪酰基乙酰化酶/去饱和酶
  • DOI:
    10.1046/j.1432-1327.2000.01418.x
  • 发表时间:
    2000
  • 期刊:
  • 影响因子:
    5.4
  • 作者:
    P. Sperling;Michael Lee;T. Girke;U. Zähringer;S. Stymne;E. Heinz
  • 通讯作者:
    E. Heinz
LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice[S]
LCAT 缺乏不会损害 APP/PS1 小鼠的淀粉样蛋白代谢[S]
  • DOI:
  • 发表时间:
    2014
  • 期刊:
  • 影响因子:
    6.5
  • 作者:
    S. Stukas;L. Freeman;Michael Lee;Anna Wilkinson;A. Ossoli;B. Vaisman;S. Demosky;Jeniffer Y. Chan;Veronica Hirsch;A. Remaley;C. Wellington
  • 通讯作者:
    C. Wellington
In vitro assessment of clastogenicity of mobile‐phone radiation (835 MHz) using the alkaline comet assay and chromosomal aberration test
使用碱性彗星试验和染色体畸变试验体外评估手机辐射(835 MHz)的致畸性
  • DOI:
    10.1002/tox.20347
  • 发表时间:
    2008
  • 期刊:
  • 影响因子:
    4.5
  • 作者:
    Ji;Sae;Young;S. Yu;W. Koh;Joong‐Rak Hong;Taeho Son;Sung;Michael Lee
  • 通讯作者:
    Michael Lee
Paclitaxel-Induced G2/M Arrest via Different Mechanism of Actions in Glioma Cell Lines with Differing p53 Mutational Status
紫杉醇通过不同作用机制在不同 p53 突变状态的胶质瘤细胞系中诱导 G2/M 期停滞
  • DOI:
  • 发表时间:
    2016
  • 期刊:
  • 影响因子:
    0
  • 作者:
    B. Han;Michael Lee
  • 通讯作者:
    Michael Lee

Michael Lee的其他文献

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{{ truncateString('Michael Lee', 18)}}的其他基金

WORKSHOP: VL/HCC 2020 Graduate Consortium
研讨会:VL/HCC 2020 毕业生联盟
  • 批准号:
    2041418
  • 财政年份:
    2020
  • 资助金额:
    $ 3.51万
  • 项目类别:
    Standard Grant
Increasing Urban Youth Participation in Computing through Mentorship and Coding Resources
通过指导和编码资源增加城市青年对计算的参与
  • 批准号:
    1837489
  • 财政年份:
    2019
  • 资助金额:
    $ 3.51万
  • 项目类别:
    Standard Grant
CRII: Cyberlearning: Keeping Computer Programming Learners Engaged Online
CRII:网络学习:让计算机编程学习者在线参与
  • 批准号:
    1657160
  • 财政年份:
    2017
  • 资助金额:
    $ 3.51万
  • 项目类别:
    Standard Grant
Does the potential for AMR selection differ between common UK cattle grazing systems?
英国常见牛放牧系统之间 AMR 选择的潜力是否有所不同?
  • 批准号:
    NE/N019792/1
  • 财政年份:
    2016
  • 资助金额:
    $ 3.51万
  • 项目类别:
    Research Grant
A metabonomic approach to identify biomarkers for bovine mycotoxicosis
鉴定牛霉菌中毒生物标志物的代谢组学方法
  • 批准号:
    BB/M006409/1
  • 财政年份:
    2015
  • 资助金额:
    $ 3.51万
  • 项目类别:
    Research Grant
NSF East Asia and Pacific Summer Institute for FY 2012 in Korea
NSF 东亚及太平洋地区 2012 财年韩国暑期学院
  • 批准号:
    1210205
  • 财政年份:
    2012
  • 资助金额:
    $ 3.51万
  • 项目类别:
    Fellowship Award
Exploring the basis of cannabinoid analgesia in humans
探索人类大麻素镇痛的基础
  • 批准号:
    G0601340/1
  • 财政年份:
    2007
  • 资助金额:
    $ 3.51万
  • 项目类别:
    Fellowship
Collaborative Research and Development of Prototype Java-Based Learning Materials for the Environment of Undergraduate Electrodynamics
本科生电动力学环境下基于Java的原型学习资料的协同研发
  • 批准号:
    0127438
  • 财政年份:
    2002
  • 资助金额:
    $ 3.51万
  • 项目类别:
    Standard Grant
Evaluating models of category learning that use general feature-based representations
评估使用基于通用特征的表示的类别学习模型
  • 批准号:
    ARC : DP0211406
  • 财政年份:
    2002
  • 资助金额:
    $ 3.51万
  • 项目类别:
    Discovery Projects
Computer Science, Engineering, and Mathematics Scholarships Program
计算机科学、工程和数学奖学金计划
  • 批准号:
    9987171
  • 财政年份:
    2000
  • 资助金额:
    $ 3.51万
  • 项目类别:
    Standard Grant

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水稻边界发育缺陷突变体abnormal boundary development(abd)的基因克隆与功能分析
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