Imine Reductases: Biochemistry, Engineering and Application
亚胺还原酶:生物化学、工程与应用
基本信息
- 批准号:BB/M006611/1
- 负责人:
- 金额:$ 39.5万
- 依托单位:
- 依托单位国家:英国
- 项目类别:Research Grant
- 财政年份:2015
- 资助国家:英国
- 起止时间:2015 至 无数据
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
目前,GtR 中尚未提供所有资助研究的摘要。这通常是因为在提交提案时不需要摘要,但可能是因为它包含个人详细信息等敏感信息。
项目成果
期刊论文数量(10)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Combined Imine Reductase and Amine Oxidase Catalyzed Deracemization of Nitrogen Heterocycles
- DOI:10.1002/cctc.201500822
- 发表时间:2016-01-07
- 期刊:
- 影响因子:4.5
- 作者:Heath, Rachel S.;Pontini, Marta;Turner, Nicholas J.
- 通讯作者:Turner, Nicholas J.
Enantioselective Synthesis of Chiral Vicinal Amino Alcohols Using Amine Dehydrogenases
使用胺脱氢酶对映选择性合成手性邻氨基醇
- DOI:10.1021/acscatal.9b03889
- 发表时间:2019-12-01
- 期刊:
- 影响因子:12.9
- 作者:Chen, Fei-Fei;Cosgrove, Sebastian C.;Turner, Nicholas J.
- 通讯作者:Turner, Nicholas J.
Kinetic Resolution and Deracemization of Racemic Amines Using a Reductive Aminase
- DOI:10.1002/cctc.201701484
- 发表时间:2018-02-07
- 期刊:
- 影响因子:4.5
- 作者:Aleku, Godwin A.;Mangas-Sanchez, Juan;Turner, Nicholas J.
- 通讯作者:Turner, Nicholas J.
Identification of Novel Bacterial Members of the Imine Reductase Enzyme Family that Perform Reductive Amination
- DOI:10.1002/cctc.201701408
- 发表时间:2018-02-07
- 期刊:
- 影响因子:4.5
- 作者:France, Scott P.;Howard, Roger M.;Turner, Nicholas J.
- 通讯作者:Turner, Nicholas J.
Biocatalytic Routes to Enantiomerically Enriched Dibenz[ c , e ]azepines
富含对映体的二苯并[c,e]氮杂卓类化合物的生物催化路线
- DOI:10.1002/ange.201708453
- 发表时间:2017
- 期刊:
- 影响因子:0
- 作者:France S
- 通讯作者:France S
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Nicholas Turner其他文献
Pilot randomised controlled trial of school‐based humanistic counselling for psychological distress in young people: Outcomes and methodological reflections
青少年心理困扰校本人文咨询随机对照试验:结果与方法学反思
- DOI:
10.1080/14733145.2014.905614 - 发表时间:
2014 - 期刊:
- 影响因子:2.4
- 作者:
J. Pybis;M. Cooper;A. Hill;Karen Cromarty;Ruth Levesley;J. Murdoch;Nicholas Turner - 通讯作者:
Nicholas Turner
Mental health support and training to improve secondary school teachers’ well-being: the WISE cluster RCT
心理健康支持和培训以改善中学教师的福祉:WISE 集群随机对照试验
- DOI:
10.3310/phr09120 - 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
J. Kidger;Rhiannon Evans;S. Bell;H. Fisher;Nicholas Turner;W. Hollingworth;S. Harding;Jillian Powell;R. Brockman;L. Copeland;R. Araya;R. Campbell;T. Ford;D. Gunnell;Richard Morris;S. Murphy - 通讯作者:
S. Murphy
A multi-centre, three-arm, individually randomised, non-inferiority, open trial to compare immediate orally administered, immediate topically administered or delayed orally administered antibiotics for acute otitis media with discharge in children: The Runny Ear Study (REST): study protocol. Trials,
一项多中心、三组、单独随机、非劣效性、开放性试验,比较立即口服、立即局部给药或延迟口服抗生素治疗有分泌物的儿童急性中耳炎:流涕研究(REST):研究
- DOI:
- 发表时间:
2020 - 期刊:
- 影响因子:0
- 作者:
K. Curtis;M. Moore;C. Cabral;V. Curcin;J. Horwood;R. Morris;Vibhore Prasad;A. Schilder;Nicholas Turner;S. Wilkes;A. Hay;Jodi Taylor - 通讯作者:
Jodi Taylor
Alpelisib plus fulvestrant in emPIK3CA/em-mutated, hormone receptor-positive advanced breast cancer after a CDK4/6 inhibitor (BYLieve): one cohort of a phase 2, multicentre, open-label, non-comparative study
阿培利司联合氟维司群治疗 emPIK3CA/雌激素受体突变、激素受体阳性晚期乳腺癌(在 CDK4/6 抑制剂治疗后)(BYLieve):一项 2 期、多中心、开放标签、非对照研究的一个队列
- DOI:
10.1016/s1470-2045(24)00673-9 - 发表时间:
2024-12-01 - 期刊:
- 影响因子:35.900
- 作者:
Hope S Rugo;Florence Lerebours;Eva Ciruelos;Pamela Drullinsky;Manuel Ruiz-Borrego;Patrick Neven;Yeon Hee Park;Aleix Prat;Thomas Bachelot;Dejan Juric;Nicholas Turner;Nickolas Sophos;Juan Pablo Zarate;Christina Arce;Yu-Ming Shen;Stuart Turner;Hemanth Kanakamedala;Wei-Chun Hsu;Stephen Chia - 通讯作者:
Stephen Chia
P124. Avoiding surgery in breast cancer patients with exceptional Response to neo-adjuvant chemotherapy - ASTARTE Trial
- DOI:
10.1016/j.ejso.2019.01.144 - 发表时间:
2019-05-01 - 期刊:
- 影响因子:
- 作者:
Marios Konstantinos Tasoulis;Gillian Ross;Nicholas Turner;Navita Somaiah;Romney Pope;Steve Allen;Peter Barry;Jennifer Rusby;Ashutosh Nerurkar;Peter Osin;Fiona MacNeill - 通讯作者:
Fiona MacNeill
Nicholas Turner的其他文献
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{{ truncateString('Nicholas Turner', 18)}}的其他基金
New Synthetic Chaperones to Enhance Protein Activity
增强蛋白质活性的新型合成伴侣
- 批准号:
EP/V056085/2 - 财政年份:2023
- 资助金额:
$ 39.5万 - 项目类别:
Fellowship
Directed Molecular Recognition through Next-Generation Hybrid Molecular Imprinting
通过下一代混合分子印迹进行定向分子识别
- 批准号:
EP/V046594/2 - 财政年份:2023
- 资助金额:
$ 39.5万 - 项目类别:
Research Grant
New Synthetic Chaperones to Enhance Protein Activity
增强蛋白质活性的新型合成伴侣
- 批准号:
EP/V056085/1 - 财政年份:2022
- 资助金额:
$ 39.5万 - 项目类别:
Fellowship
Biocatalytic Manufacturing of Nucleic Acid Therapeutics
核酸治疗药物的生物催化制造
- 批准号:
MR/W029324/1 - 财政年份:2022
- 资助金额:
$ 39.5万 - 项目类别:
Research Grant
Production of Niraparib using Imine Reductases
使用亚胺还原酶生产尼拉帕尼
- 批准号:
BB/V003410/1 - 财政年份:2021
- 资助金额:
$ 39.5万 - 项目类别:
Research Grant
Directed Molecular Recognition through Next-Generation Hybrid Molecular Imprinting
通过下一代混合分子印迹进行定向分子识别
- 批准号:
EP/V046594/1 - 财政年份:2021
- 资助金额:
$ 39.5万 - 项目类别:
Research Grant
Exploration of Linking Chemistry in the Design of Aptamer-Molecularly Imprinted Polymer Hybrids (aptaMIPs)
适配体分子印迹聚合物杂化物 (aptaMIPs) 设计中连接化学的探索
- 批准号:
EP/S003339/1 - 财政年份:2019
- 资助金额:
$ 39.5万 - 项目类别:
Research Grant
Centre for Biocatalytic Manufacture of New Modalities (CBNM)
新模式生物催化制造中心(CBNM)
- 批准号:
EP/S005226/1 - 财政年份:2018
- 资助金额:
$ 39.5万 - 项目类别:
Research Grant
Novel Biocatalysts for Improved Routes to an Active Pharmaceutical Ingredient
用于改进活性药物成分路线的新型生物催化剂
- 批准号:
BB/N010736/1 - 财政年份:2016
- 资助金额:
$ 39.5万 - 项目类别:
Research Grant
Biocatalysis & Biotransformation: A 5th Theme for the National Catalysis Hub
生物催化
- 批准号:
EP/M013219/1 - 财政年份:2015
- 资助金额:
$ 39.5万 - 项目类别:
Research Grant
相似海外基金
21ENGBIO: In Cell Assembly of Artificial Imine Reductases for Whole-Cell Catalysis
21ENGBIO:用于全细胞催化的人工亚胺还原酶的细胞内组装
- 批准号:
BB/W011131/1 - 财政年份:2023
- 资助金额:
$ 39.5万 - 项目类别:
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Differential regulation of three DMSO reductases during enteric salmonellosis
肠道沙门氏菌病过程中三种 DMSO 还原酶的差异调节
- 批准号:
10749408 - 财政年份:2023
- 资助金额:
$ 39.5万 - 项目类别:
5a-Reductases: Mapping pathways of Metabolic Disease
5a-还原酶:绘制代谢疾病的途径
- 批准号:
2746668 - 财政年份:2022
- 资助金额:
$ 39.5万 - 项目类别:
Studentship
Production of Niraparib using Imine Reductases
使用亚胺还原酶生产尼拉帕尼
- 批准号:
BB/V003410/1 - 财政年份:2021
- 资助金额:
$ 39.5万 - 项目类别:
Research Grant
The global regulation of dynamics and structure mediated by single hydride in a family of reductases
还原酶家族中单个氢化物介导的动力学和结构的全局调节
- 批准号:
10296136 - 财政年份:2021
- 资助金额:
$ 39.5万 - 项目类别:
How Distinct are the two Chiral Sulfur Epimers of Amyloid Beta Met35 Sulfoxide in their Aggregation, Toxicity and Reactivity with Methionine Sulfoxide Reductases A and B?
淀粉样蛋白 Beta Met35 亚砜的两种手性硫差向异构体在聚集、毒性以及与蛋氨酸亚硫酸还原酶 A 和 B 的反应性方面有何不同?
- 批准号:
10360472 - 财政年份:2021
- 资助金额:
$ 39.5万 - 项目类别:
The global regulation of dynamics and structure mediated by single hydride in a family of reductases
还原酶家族中单个氢化物介导的动力学和结构的全局调节
- 批准号:
10656573 - 财政年份:2021
- 资助金额:
$ 39.5万 - 项目类别:
Development of adjuvant for treatment of hormone-dependent cancers targeted to aldo-keto reductases
开发针对醛酮还原酶的激素依赖性癌症治疗佐剂
- 批准号:
20K07033 - 财政年份:2020
- 资助金额:
$ 39.5万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Characterization of bacterial reductases acting on the A-ring of 11-oxy-androgens
作用于 11-氧雄激素 A 环的细菌还原酶的表征
- 批准号:
10653436 - 财政年份:2020
- 资助金额:
$ 39.5万 - 项目类别:
Structural Dynamics of Nitric Oxide Reductases Srudied by Time-Resolved Techniques
通过时间分辨技术研究一氧化氮还原酶的结构动力学
- 批准号:
19H00926 - 财政年份:2019
- 资助金额:
$ 39.5万 - 项目类别:
Grant-in-Aid for Scientific Research (A)














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