HIGH-SPEED MRI TUMOR IMAGING

提出了一种腹部和胸部肿瘤成像系统。 虽然 磁共振成像提供了良好的软组织对比，在一个非侵入性无毒 时尚，好处主要是在那些领域，可以 成功固定。 因此，头部，骨盆，脊柱，四肢等。 可以稳定扫描几分钟 腹部和胸部的图像 被严重的呼吸伪影所困扰 我们建议提供这些 通过采集数据， 在屏气间隔内。 这是由一个新的系统完成的 利用k空间的一组交错方形螺旋扫描。 这种独特 方法，这已经成功地实现，获取数据，在一个 使用常规MRI成像系统。 拟议的快速成像系统将得到加强， 重要特征。 肿瘤通常难以可视化，因为它们 特征与周围组织相似。 对比度 通过使用非常晚的回波显著改善，但是遭受过量的 噪声 图像可以使用一个系统进行深刻的改进， “相关”滤波，其中使用低噪声早期回波来增强 高对比度晚期回声图像。 改进的其他重要特征 肿瘤图像包括用于肿瘤血管分布的流动成像、稳健的分离 水和脂肪，以及自聚焦激发，使成像， 具有极短弛豫时间的材料。 肺等组织 实质，这是正常情况下是不可见的，可以成像与此 approach.

A system of tumor imaging of the abdomen and thorax is proposed. Although MRI has provided excellent soft tissue contrast in a non-invasive non-toxic fashion, the benefits have accrued primarily in those areas which can be successfully immobilized. Thus the head, pelvis, spine, extremities etc. can be stabilized for a few minute scan. Images of the abdomen and thorax are plagued by severe breathing artifacts. We propose to provide these benefits to all areas of the abdomen and thorax by acquiring the data within a breath-holding interval. This is accomplished by a novel system utilizing a set of interleaved square spiral scans of k-space. This unique approach, which has been successfully implemented, acquires the data in a few seconds using conventional MRI imaging systems. The proposed fast imaging system will be enhanced with a number of important features. Tumors are often difficult to visualize because their characteristics are similar to surrounding tissue. The contrast is significantly improving by using very late echoes, but suffer from excess noise. The images can be profoundly improved using a system of "correlative" filtering where a low-noise early echo is used to enhance the high-contrast late echo image. Other important features of the improved tumor images include flow imaging for tumor vascularity, robust separation of water and fat, and self-focusing excitations which enable the imaging of materials with extremely short relaxation times. Tissues such as lung parenchyma, which is normally not visualized, can be imaged with this approach.