Understanding the reprogramming of host mRNA translation during calicivirus infection

了解杯状病毒感染期间宿主 mRNA 翻译的重编程

• 批准号: BB/N001176/1
• 负责人: Ian Goodfellow
• 金额: $ 40.47万
• 依托单位: University of Cambridge
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2016
• 资助国家: 英国
• 起止时间: 2016 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FN001176%2F1
• 关键词: Understanding; reprogramming; host; mRNA; translation

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Norovirus infection results in assembly of virus-specific G3BP1 granules and evasion of eIF2a signaling

诺如病毒感染导致病毒特异性 G3BP1 颗粒组装并逃避 eIF2a 信号传导

• DOI: 10.1101/490318
• 发表时间: 2018
• 作者: Brocard M

Murine Norovirus Infection Results in Anti-inflammatory Response Downstream of Amino Acid Depletion in Macrophages.

• DOI: 10.1128/jvi.01134-21
• 发表时间: 2021-09-27
• 期刊: Journal of virology
• 影响因子: 5.4
• 作者: Brocard M;Lu J;Hall B;Borah K;Moller-Levet C;Georgana I;Sorgeloos F;Beste DJV;Goodfellow IG;Locker N
• 通讯作者: Locker N

Virus genomes reveal factors that spread and sustained the Ebola epidemic.

• DOI: 10.1038/nature22040
• 发表时间: 2017-04-20
• 期刊: Nature
• 影响因子: 64.8
• 作者: Dudas G;Carvalho LM;Bedford T;Tatem AJ;Baele G;Faria NR;Park DJ;Ladner JT;Arias A;Asogun D;Bielejec F;Caddy SL;Cotten M;D'Ambrozio J;Dellicour S;Di Caro A;Diclaro JW;Duraffour S;Elmore MJ;Fakoli LS;Faye O;Gilbert ML;Gevao SM;Gire S;Gladden-Young A;Gnirke A;Goba A;Grant DS;Haagmans BL;Hiscox JA;Jah U;Kugelman JR;Liu D;Lu J;Malboeuf CM;Mate S;Matthews DA;Matranga CB;Meredith LW;Qu J;Quick J;Pas SD;Phan MVT;Pollakis G;Reusken CB;Sanchez-Lockhart M;Schaffner SF;Schieffelin JS;Sealfon RS;Simon-Loriere E;Smits SL;Stoecker K;Thorne L;Tobin EA;Vandi MA;Watson SJ;West K;Whitmer S;Wiley MR;Winnicki SM;Wohl S;Wölfel R;Yozwiak NL;Andersen KG;Blyden SO;Bolay F;Carroll MW;Dahn B;Diallo B;Formenty P;Fraser C;Gao GF;Garry RF;Goodfellow I;Günther S;Happi CT;Holmes EC;Kargbo B;Keïta S;Kellam P;Koopmans MPG;Kuhn JH;Loman NJ;Magassouba N;Naidoo D;Nichol ST;Nyenswah T;Palacios G;Pybus OG;Sabeti PC;Sall A;Ströher U;Wurie I;Suchard MA;Lemey P;Rambaut A
• 通讯作者: Rambaut A

Norovirus-Mediated Modification of the Translational Landscape via Virus and Host-Induced Cleavage of Translation Initiation Factors.

• DOI: 10.1074/mcp.m116.062448
• 发表时间: 2017-04
• 期刊: Molecular & cellular proteomics : MCP
• 作者: Emmott E;Sorgeloos F;Caddy SL;Vashist S;Sosnovtsev S;Lloyd R;Heesom K;Locker N;Goodfellow I
• 通讯作者: Goodfellow I

Murine Norovirus Infection Results in Anti-inflammatory Response Downstream of Amino Acid Depletion in Macrophages

• DOI: 10.1128/jvi.01134-21.4
• 发表时间: 2021-10-01
• 期刊: JOURNAL OF VIROLOGY
• 影响因子: 5.4
• 作者: Brocard, Michele;Lu, Jia;Locker, Nicolas
• 通讯作者: Locker, Nicolas