Accelerated Breeding for Disease Resistance in Commercial Brassicas by Associative Transcriptomics

通过关联转录组学加速商业芸苔属抗病育种

• 批准号: BB/N01331X/1
• 负责人: Christopher Ridout
• 金额: $ 14.41万
• 依托单位: John Innes Centre
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2016
• 资助国家: 英国
• 起止时间: 2016 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FN01331X%2F1
• 关键词: Accelerated; Breeding; Disease; Resistance; Commercial

Baby Leaf Kale (BLK) has been popularised as a super food, through the growing health awareness and weight loss movement in the USA and Europe. Consequently, the demand for BLK has increased with global consumption rising by 40% in just one year (2012 - 2013). Diseases caused by mildews and bacteria are a major problem in BLK production. This problem has become even more challenging due to enforced reductions in agrochemical use as a result of changing legislation in early 2015. There are also tight restrictions on the Minimal Residue Level (MRL) of pesticides and fungicides which are defined product by product and frequently reviewed. CN Seeds is a UK-based commercial seed breeding company specializing in breeding baby leaf salad seeds, including BLK and herb seeds. BLK has been the company's best-selling product over the last two years, accounting for 12% of total revenues. The continual introduction of new varieties that meet and exceed customer needs is a key component of CN Seeds competitive strategy. This interchange project addresses the challenge of developing disease-resistance with a commercially desirable BLK variety by transferring knowledge between scientists at JIC and CN Seeds. The JIC scientists are working on developing disease resistance in oilseed rape, an important brassica closely related to BLK. The methods that they are using for variety improvement in oilseed rape can be directly applied to BLK, and this interchange aims to transfer that knowledge. The JIC scientists will visit CN Seeds to learn about commercial production of seed for the leaf salad market and the constraints imposed by diseases. This will enable them to tailor their research to address this issue more effectively. A CN Seeds scientist will also work at JIC, learning how to develop disease-resistance screening procedures and about a novel breeding technique known as associative transcriptomics. This genetic technique rapidly identifies gene loci associated with disease resistance which can be used to develop molecular markers for accelerated breeding.The interchange benefits both JIC and UK science generally through improved understanding of the commercial constraints on seed production; this will enable researchers to target their science to achieve greater impact. The interchange is supported financially by CN Seeds which benefits through improved competitiveness against overseas rivals, increasing exports and revenue for the UK economy.

随着美国和欧洲健康意识的增强和减肥运动的开展，婴儿羽衣甘蓝(BLK)作为一种超级食品已经流行起来。因此，对BLK的需求增加了，全球消费在短短一年内(2012-2013)增长了40%。霉菌和细菌引起的疾病是BLK生产中的一个主要问题。由于2015年初改变立法，强制减少了农用化学品的使用，这一问题变得更加具有挑战性。对农药和杀菌剂的最低残留水平(MRL)也有严格的限制，这些标准是逐个产品定义的，并经常得到审查。CN Seeds是一家总部位于英国的商业种子育种公司，专门培育婴儿叶沙拉种子，包括BLK和药草种子。过去两年，BLK一直是该公司最畅销的产品，占总收入的12%。不断推出满足和超过客户需求的新品种是CN Seed竞争战略的关键组成部分。这一交流项目通过在JIC和CN Seed的科学家之间传递知识，解决了用商业上希望的BLK品种开发抗病能力的挑战。JIC的科学家们正在致力于开发油菜的抗病能力，油菜是一种与BLK密切相关的重要油菜。他们用于油菜品种改良的方法可以直接应用于BLK，这次交流的目的是传递这种知识。JIC的科学家们将访问CN Seeds，以了解叶沙拉市场种子的商业生产情况，以及疾病造成的限制。这将使他们能够调整他们的研究，以更有效地解决这个问题。CN Seeds的一名科学家也将在JIC工作，学习如何开发抗病筛选程序，以及一种名为联合转录组的新育种技术。这种遗传技术快速识别与抗病相关的基因座，可用于开发加速育种的分子标记。交流通过改善对种子生产的商业限制的理解，使JIC和英国科学总体上受益；这将使研究人员能够针对他们的科学实现更大的影响。这一交换得到了CN Seed的财务支持，该公司通过提高相对于海外竞争对手的竞争力、增加英国经济的出口和收入而受益。