Glycointeractions

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This project aims to characterise two new classes of structural interactions with carbohydrates: carbohydrate-carbohydrate interactions and short alpha helical domains which can bind carbohydrates. Carbohydrate structures are found on the surface of cells in all forms of life. The intended outcome is to understand the molecular basis for these carbohydrate interactions. This information should provide an intellectual framework for understanding and manipulating these carbohydrate interactions, which underpin many processes in biological systems. The findings will inform the design of future drugs to block these interactions and will generate new tools for glycoscience.