Targeting glycointeractions to generate new opportunities to treat and prevent bacterial infections.
Targeting glycointeractions to generate new opportunities to treat and prevent bacterial infections.
批准号:
nhmrc : 1138466
负责人:
Prof Michael Jennings
金额:
$52.37万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2022-12-31
中文摘要
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英文摘要
Bacteria and bacterial toxins can interact with complex sugar structures on human cells called glycans. My research team has identified new and important glycan interactions used by bacteria that cause diseases ranging from pneumonia, meningitis and food borne infections to urinary tract and sexually transmitted diseases. Now that these interactions have been discovered, they can be exploited to create drugs and vaccines that may treat and prevent disease by blocking the glycan interactions.
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会议论文
A “Goldilocks” live attenuated poultry vaccine for Infectious Coryza
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批准号:LP210301365
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项目类别:Linkage Projects
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资助金额:$44.35万
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财政年份:2023
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负责人:Prof Michael Jennings
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依托单位:
Genetic Basis of Variable Expression of Glycan Xeno-Autoantigens by Cattle
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批准号:DP200103734
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项目类别:Discovery Projects
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资助金额:$33.72万
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财政年份:2020
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负责人:Prof Michael Jennings
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依托单位:
Targeting glycointeractions to generate new opportunities to treat and prevent bacterial infections.
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批准号:nhmrc : GNT1138466
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项目类别:Research Fellowships
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资助金额:$77.45万
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财政年份:2018
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负责人:Prof Michael Jennings
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依托单位:
Glycointeractions
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批准号:DP170104692
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项目类别:Discovery Projects
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资助金额:$32.38万
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财政年份:2017
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负责人:Prof Michael Jennings
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依托单位:
The molecular mechanism of action of bacterial epigenetic regulators
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批准号:DP170104691
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项目类别:Discovery Projects
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资助金额:$29.94万
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财政年份:2017
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负责人:Prof Michael Jennings
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依托单位:
The protein O-glycosylation pathway of Neisseria: a model system for O-glycosylation of bacterial proteins with potential use in biotechnology
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批准号:DP130103141
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项目类别:Discovery Projects
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资助金额:$24.52万
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财政年份:2013
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负责人:Prof Michael Jennings
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依托单位:
The protein O-glycosylation pathway in Neisseria meningitidis
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批准号:DP110101058
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项目类别:Discovery Projects
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资助金额:$11.18万
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财政年份:2011
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负责人:Prof Michael Jennings
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依托单位:
Role in disease and vaccine potential of cell surface o-linked glycoproteins in pathogenic Neisseria.
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批准号:nhmrc : 569737
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项目类别:NHMRC Project Grants
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资助金额:$14.16万
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财政年份:2009
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负责人:Prof Michael Jennings
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依托单位:
Phasevarions of pathogenic Neisseria
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批准号:nhmrc : 519704
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项目类别:NHMRC Project Grants
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资助金额:$37.2万
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财政年份:2008
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负责人:Prof Michael Jennings
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依托单位:
Phasevarions of Haemophilus influenzae: mechanisms and origins of a novel epigenetic system controlling coordinated random switching in expression of multiple genes
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批准号:DP0879604
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项目类别:Discovery Projects
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资助金额:$40.02万
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财政年份:2008
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负责人:Prof Michael Jennings
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依托单位:
Novel vaccines and serotyping scheme for Haemophilus parasuis
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批准号:LP0218929
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项目类别:Linkage Projects
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资助金额:$12.97万
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财政年份:2002
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负责人:Prof Michael Jennings
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依托单位:
Glycosylation of pili in pathogenic Neisseria: function in disease and potential as a vaccine antigen
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批准号:nhmrc : 210310
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项目类别:NHMRC Project Grants
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资助金额:$10.06万
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财政年份:2002
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负责人:Prof Michael Jennings
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依托单位:
Molecular mechanisms of pilin glycosylation in Neisseria: a model system for protein glycosylation in bacteria.
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批准号:DP0210205
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项目类别:Discovery Projects
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资助金额:$18.23万
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财政年份:2002
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负责人:Prof Michael Jennings
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依托单位:
Characterisation of HiaNm, a novel outer membrane from Neisseria meningitidis; vaccine potential and functional studies
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批准号:nhmrc : 102599
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项目类别:NHMRC Project Grants
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资助金额:$23.78万
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财政年份:2000
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负责人:Prof Michael Jennings
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依托单位:
Phase variation of LPS expression in Neisseria meningitidis; role in pathogenesis and vaccine development.
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批准号:nhmrc : 991266
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项目类别:NHMRC Project Grants
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资助金额:$11.61万
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财政年份:1999
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负责人:Prof Michael Jennings
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依托单位:
Genetics and biochemistry of pili glycosylation in pathogenic neisseria
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批准号:nhmrc : 981423
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项目类别:NHMRC Project Grants
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资助金额:$11.18万
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财政年份:1998
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负责人:Prof Michael Jennings
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依托单位:
海外基金