A LONGITUDINAL STUDY IN PSYCHIATRIC EPIDEMIOLOGY

精神病流行病学的纵向研究

• 批准号: 3377431
• 负责人: JANE M MURPHY
• 金额: $ 16.78万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1984
• 资助国家: 美国
• 起止时间: 1984-09-30 至 1990-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3377431
• 关键词: Canada; adult human (21+); clinical anxiety; computers; disease /disorder proneness /risk; human subject; longitudinal human study; mental health epidemiology; questionnaires; rural area

This application concerns the completion of a longitudinal study of psychiatric epidemiology as it relates to data already collected for the period 1952 to 1970 and then extension through the gathering of new data about the period 1970 to 1990. Named the Stirling County Study, the investigation involves multiple cross- sectional surveys and several cohort follow-up studies pertinent to 2848 adult residents of a rapidly changing rural environment in Atlantic Canada. The objectives of the study are to contribute information on trends in prevalence, incidence, outcomes (mortality and morbidity), and treatment of psychiatric disorders in a general population and to relate these variables to risk factors about physical health, life events, and social conditions. The data consist in: 1) self-report of symptoms, impairment, and duration of depression and anxiety disorders through structured questionnaire interviews; 2) reports by general physicians about the full range of psychiatric disorders; 3) a case register of a local mental health center; and 4) death certificates. A diagnostic computer program was written for analyzing information given by subjects. Using this methodology, it was found that during the period from 1952 through 1970 the prevalence of depression and anxiety remained at a stable rate of 12 cases per 100 persons and the incidence of these disorders was, on the average, nine cases per 1000 persons per year. Depression has consistently been distinguished from anxiety, including the fact that depression was found to have significantly worse outcome in terms of both mortality and morbidity. Life table methods, log-linear analysis, and survival regressions are used for calculating rates and testing the significance of associations with risk factors. The application includes research directed toward comparing findings from this investigation with those from other places study, both urban and rural. The degree of concordance between the interview methods of this study and those of more recent studies will be assessed by using the Diagnostic Interview Schedule along with the Stirling Study Schedule in the follow-up interviews to be carried out in 1990.

这项申请涉及一项纵向研究的完成 因为它与已经收集的数据有关 从1952年到1970年，然后延长到 收集1970年至1990年期间的新数据。命名为 斯特林县的研究，调查涉及多个交叉- 与以下方面相关的横断面调查和几项队列跟踪研究 中国快速变化的农村环境中的2848名成年居民 大西洋加拿大。 这项研究的目的是提供以下方面的信息 流行率、发病率、结局的趋势(死亡率和 发病率)，以及一般精神疾病的治疗 并将这些变量与以下风险因素联系起来 身体健康、生活事件和社会状况。数据 包括：1)症状、损害和持续时间的自我报告 通过结构化研究抑郁症和焦虑症 问卷访谈；2)全科医生报告 精神疾病的全部范围；3)当地的病例登记簿 精神健康中心；4)死亡证明。 编写了用于分析的诊断计算机程序 受试者提供的信息。使用这种方法，它是 发现在1952年至1970年期间 抑郁和焦虑的患病率保持在稳定的 每百人12例，这些疾病的发病率为， 平均每年每1000人中有9例。抑郁症 一直与焦虑区分开来，包括 事实是，抑郁症被发现明显恶化 在死亡率和发病率方面的结果。生命表 方法、对数线性分析和生存回归分析用于 计算比率并测试关联的重要性 风险因素。 应用程序包括针对比较的研究 这次调查的结果与其他地方的调查结果 无论是城市还是农村，都要学习。两国之间的协调程度 本研究的访谈方法和最新的访谈方法 研究将通过诊断性访谈进行评估 与后续的斯特林研究时间表一起进行 面谈将于1990年进行。