LONGITUDINAL STUDY IN PSYCHIATRIC EPIDEMIOLOGY

精神病流行病学的纵向研究

• 批准号: 2244793
• 负责人: JANE M MURPHY
• 金额: $ 55.94万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1984
• 资助国家: 美国
• 起止时间: 1984-09-30 至 1995-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2244793
• 关键词: Canada; clinical anxiety; clinical depression; cognition disorders; computer assisted diagnosis; disease /disorder proneness /risk; human subject; longitudinal human study; mental health epidemiology; prognosis; relapse /recurrence; rural area; statistics /biometry; urban area

This application concerns the extension of a longitudinal study in psychiatric epidemiology (the Stirling County Study in Atlantic Canada) so that it will provide a 40-year perspective on the prevalence, incidence, clinical outcomes, and mortality risk associated with psychiatric disorders. Consistent data-collection procedures were used to study representative samples of adults in 1952, 1962-64, and 1970. In each field phase after the first, the same procedures were used to conduct follow-up investigations of individuals who had entered the study earlier. These procedures involve interviewing subjects with a structured schedule that covers depression, anxiety, physical health, and socio-demographic factors along with interviewing general physicians about the psychiatric and medical histories of the same subjects. The specific aims of the research are to: 1.) select and investigate a new sample of 1350 subjects representing the adults of Stirling County in 1992; 2.) locate and re-interview 1400 former subjects expected to be alive in 1992; 3.) gather mortality information about the approximately 950 former subjects who can be expected to have died; and 4). expand the interview protocol to include portions of the Diagnostic Interview Schedule (DIS) and, for persons 65 years and older, the Modified Mini-Mental State Examination. The purpose of the latter additions is to lay the foundation for comparing findings from this study with those from the five U.S. sites of NIMH's Epidemiologic Catchment Area (ECA) Program, those from a similar study in Edmonton, Canada, and those to be derived from a national study in Canada of the epidemiology of cognitive impairment. Diagnostic computer programs are available for analyzing information from subjects, and computer-aided procedures have been prepared for categorizing the data given by physicians. Lifetable methods, log linear analysis, and survival regressions will be used for calculating rates and testing the significance of associations with risk factors. The main objective of the research is to provide information about the epidemiology of psychiatric disorders over time in one place of study while also comparing findings from this one place to those from other areas where similar research has been conducted.

这项申请涉及到一项纵向研究的扩展 精神流行病学(加拿大大西洋的斯特林县研究) 它将提供40年的流行率，发病率， 与精神疾病相关的临床结果和死亡风险 精神错乱。使用一致的数据收集程序来研究 1952年、1962年-和1970年成人的代表性样本。在每个领域 第一阶段后，采用相同的程序进行随访 对早些时候进入研究的个人进行调查。这些 程序包括按照有组织的时间表采访受试者 涵盖抑郁、焦虑、身体健康和社会人口因素 同时采访全科医生关于精神病学和 相同科目的病史。 研究的具体目的是：1)选择并调查新的 1992年代表斯特林县成年人的1350名样本； 2.)找到并重新采访1400名预计在世的前受试者 1992年；3.)收集关于大约950名前患者的死亡信息 可能已经死亡的受试者；以及4)。扩大采访范围 包括部分诊断性面谈时间表(DIS)的协议 对于65岁及以上的人，修改后的迷你精神状态 考试。后一项补充的目的是为了奠定基础 将这项研究的结果与美国五个网站的结果进行比较 NIMH的流行病学集水区(ECA)计划，来自类似的 在加拿大埃德蒙顿的研究，以及将从国家研究中得出的结论 在加拿大，认知障碍的流行病学研究。 诊断计算机程序可用于分析来自 科目，并已准备好计算机辅助程序进行分类 医生给出的数据。生命表方法、对数线性分析和 生存回归将被用于计算死亡率和测试 与风险因素相关的重要性。 这项研究的主要目的是提供有关 在一个研究地点随着时间的推移精神疾病的流行病学 还将这一地区的调查结果与其他地区的调查结果进行比较 类似的研究也曾进行过。