A LONGITUDINAL STUDY IN PSYCHIATRIC EPIDEMIOLOGY

精神病流行病学的纵向研究

• 批准号: 3377435
• 负责人: JANE M MURPHY
• 金额: $ 14.41万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1984
• 资助国家: 美国
• 起止时间: 1984-09-30 至 1987-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3377435
• 关键词: adult human (21+); clinical anxiety; computers; human subject; longitudinal human study; mental health epidemiology; questionnaires; rural area

This application concerns the completion of analysis and reporting of a longitudinal investigation of psychiatric epidemiology, the Stirling County Study. Drawing on a combination of multiple cross-sectional surveys and several cohort follow-up investigations, the main objective is to contribute information about trends, incidence, and outcome regarding treated and untreated psychiatric disorders in a general population. The main bodies of data consist in: 1) self report of symptoms, impairment, and duration of depression and anxiety disorders through structured questionnaire interviews; and 2) reports by general physicians about the full range of psychiatric disorders. Such information was gathered between 1952 and 1970 about 2848 adult residents of a rapidly changing rural environment in eastern Canada. For the longitudinal study, computer programs were designed that substitute for earlier "clinical evaluation" procedures. The first substantive results indicate that the prevalence of depression and anxiety disorders based on self report was 12.5% in a sample surveyed in 1952 and 12.7% in another sample surveyed in 1970. The stability of these prevalence rates is noteworthy. The specific aims involved in completing the study concern: 1) validity of the new computer methods based on using the results of five annual examinations carried out face-to-face by clinical psychiatrists for a subsample of 122 adults; 2) time trend estimates of prevalence based on general physician data; 3) incidence of different types of disorders based on cohort analysis; 4) psychiatric disorder outcomes such as recovery, relapses, chronicity, disability, and mortality; 5) relationships between treated and untreated disorders drawing not only on evidence of care provided by primary physicians but also by psychiatric specialty services as indicated in a case register of a local mental health center; 6) relationships among selected risk factors (organic medical disorders, economic position, social experiences, etc.) and the incidence, duration, and outcome of different types of psychiatric disorders; and 7) evaluation of an explorative trial in prevention.

该应用程序涉及完成分析和报告 斯特林精神病学流行病学纵向调查 县研究。 绘制多个截面的组合 调查和几个队列跟踪调查，主要目标是 提供有关趋势、发生率和结果的信息 一般人群中已治疗和未治疗的精神疾病。 数据主体包括：1）症状自我报告， 损害以及抑郁症和焦虑症的持续时间 结构化问卷访谈； 2) 全科医生的报告 关于各种精神疾病。 此类信息是 1952 年至 1970 年间，大约 2848 名成年居民聚集在一个迅速发展的地区。 加拿大东部农村环境的变化。 对于纵向研究，计算机程序的设计是 替代早期的“临床评估”程序。 第一个 实质性结果表明抑郁症和焦虑症的患病率 在 1952 年调查的样本中，基于自我报告的疾病的比例为 12.5%， 1970 年调查的另一个样本为 12.7%。这些稳定性 患病率值得注意。 完成研究涉及的具体目标包括：1）有效性 新的计算机方法基于使用五年的结果 由临床精神科医生面对面进行的检查 122 名成年人的子样本； 2) 流行率的时间趋势估计基于 一般医生数据； 3) 不同类型疾病的发生率 队列分析； 4）精神疾病的结果，例如康复， 复发、慢性、残疾和死亡； 5) 之间的关系 已治疗和未治疗的疾病不仅依赖于护理证据 由初级医生提供，也由精神科专业服务提供 如当地精神卫生中心的病例登记册所示； 6） 选定的危险因素之间的关系（器质性疾病， 经济地位、社会经历等）以及发病率、持续时间、 以及不同类型精神疾病的结果； 7) 评估 预防方面的探索性试验。