Deep Protein Sequencing, Structure and Quantification Facility

深度蛋白质测序、结构和定量设施

• 批准号: LE170100192
• 负责人: Em/Prof Paul Alewood
• 金额: $ 30.01万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-05-19 至 2017-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE170100192
• 关键词: Deep; Protein; Sequencing; Structure; Quantification

This project aims to establish state-of-the-art complementary mass spectrometers to help research into molecular structure and interactions, post-translational modifications, compound stability and availability within complex biological samples. The facility’s complementary mass spectrometers combine high specificity with high sensitivity and ultrafast scanning, and are expected to rapidly discover, identify and characterise biomolecules including peptides, proteins and small molecules. The discovery of unknown compounds is expected to improve fundamental understanding of molecular structure and function, provide opportunities for new bio-industries in health and the environment, and generate commercial opportunities through spin-off companies, patents and licensing.

该项目旨在建立最先进的互补质谱仪，以帮助研究复杂生物样品中的分子结构和相互作用、翻译后修饰、化合物稳定性和可用性。该设施的补充质谱仪将高特异性、高灵敏度和超快扫描结合在一起，有望快速发现、识别和表征包括肽、蛋白质和小分子在内的生物分子。未知化合物的发现有望提高对分子结构和功能的基本了解，为健康和环境领域的新生物产业提供机会，并通过衍生公司、专利和许可创造商业机会。