High-speed multi-channel 3-D Optical Coherence Tomography studies of the biomechanics of skin friction.
High-speed multi-channel 3-D Optical Coherence Tomography studies of the biomechanics of skin friction.
批准号:
EP/K009699/1
负责人:
Stephen Matcher
金额:
$83.18万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2013
资助国家:
英国
项目状态:
已结题
起止时间:
2013 至 --
中文摘要
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英文摘要
The health of the skin has profound effects on both our physical and psychological well-being. Enormous academic and commercial effort is devoted to optimising the health and appearance of skin. The barrier function of skin has been widely studied, but less well studied is its role in providing enough friction to allow us to grip and manipulate objects. Excessive friction can produce undesirable skin conditions such as chaffing and irritation in many scenarios such as wearing a respiration face mask or the skin being in contact with a damp surface. Conversely reduction of skin friction can occur in old age and compound the difficulties experienced by the older population when gripping and manipulating objects.Many potential determinants of friction have been studied, including applied load, skin deformation, skin mechanical properties and surface textures and materials, but the sub-surface behaviour and skin strain has not been investigated as rigorously. Most of these parameters have been investigated statically and although it is known that they will change when the contact is dynamic no quantitative data is available for using in computer models of skin.The aim in this work will be to develop new imaging techniques to allow sub-surface observation of how skin behaves when it is sliding against an object and what influences this the most, for example, skin moisture, applied load, sliding speed etc. The contact area between skin and object will also studied in greater detail than before as this has a major effect on friction and as yet no techniques exist for characterising this in a moving contact.The objectives of the work will initially focus on developing the equipment and techniques needed to observe the surface and sub-surface behaviour. These will then be combined with skin testing apparatus to allow the measurements of friction etc. to be taken in parallel with the sub-surface images.The information from the tests and the techniques themselves will then be applied in three practical case studies to ensure real world impact for the work. The first will involve working with Philips on studying facial masks used by sleep apnea sufferers. Test data will help improve computer models of the contact between facial skin and a mask. The second will be carried out with Unilever and focus on characterising the effects of skin creams and cleansers. The final case study will be on using the new non-invasive imaging technique in clinical studies carried out by dermatologists at The University of Sheffield to replace tape-stripping methods currently used to study skin damage.
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DOI:
10.1038/s41598-017-13752-y
发表时间:
2017-10-17
期刊:
Scientific reports
影响因子:
4.6
作者:
[Green NH, Delaine-Smith RM, Askew HJ, Byers R, Reilly GC, Matcher SJ]
通讯作者:
Matcher SJ
New Non-invasive Techniques to Quantify Skin Surface Strain and Sub-surface Layer Deformation of Finger-pad during Sliding
量化滑动过程中指垫皮肤表面应变和次表面层变形的新型非侵入性技术
DOI:
10.1016/j.biotri.2017.07.001
发表时间:
2017
期刊:
Biotribology
影响因子:
--
作者:
[Liu X]
通讯作者:
Liu X
High speed optical coherence elastography for human skin deformation studies
用于人体皮肤变形研究的高速光学相干弹性成像
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Maiti R*]
通讯作者:
Maiti R*
The contributions of skin structural properties to the friction of human finger-pads
皮肤结构特性对人体指垫摩擦的贡献
DOI:
10.1177/1350650114567699
发表时间:
2015
期刊:
Journal of Engineering Tribology
影响因子:
--
作者:
[Liu X]
通讯作者:
Liu X
Polarization-sensitive OCT as an early predictor of spontaneous pre-term birth.
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批准号:EP/V010581/1
-
项目类别:Research Grant
-
资助金额:$107.18万
-
财政年份:2021
-
负责人:Stephen Matcher
-
依托单位:
Multi-band optical coherence tomography platform for the development of novel atopic dermatitis treatments.
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批准号:EP/S025944/1
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项目类别:Research Grant
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资助金额:$129.71万
-
财政年份:2019
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负责人:Stephen Matcher
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依托单位:
Imaging the 3-D collagen organisation of biological tissues in-vivo using polarisation-sensitive optical coherence tomography.
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财政年份:2008
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依托单位:
Feasibility of determining small vessel compliance using Doppler optical coherence tomography.
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-
财政年份:2006
-
负责人:Stephen Matcher
-
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