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Shaped Light at the Interface

Shaped Light at the Interface
界面处的异形光
批准号:
EP/M000869/1
负责人:
Kishan Dholakia
金额:
$150.82万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2014
资助国家:
英国
项目状态:
已结题
起止时间:
2014 至 --
关键词:

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中文摘要
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英文摘要
Photonics - the science and application of light- is gaining ever more prominence in both an academic and industrial setting. The Platform Grant renewal at the University of St Andrews is in the field of shaped light and applications. We would like to develop studies that will impact on biological and medical healthcare, sensing, fundamental understanding of the classical and quantum world, and even allow us to monitor the impact of global climate change upon organisms living in "harsh" environments e.g. Antarctica. In particular, we wish to develop new adventurous, risky research themes to go outside our "comfort zone" and pump prime new activities. Our work will include: i) Studies between photonics and materials science. This includes studies at the fundamental level where we will push our understanding of the classical physics of suspended micro-objects in vacuum and study the behaviour to see "quantum" effects as well as explore new directions in sensing. Imagine a sphere suspended in vacuum that is isolated from its environment. Such a sphere can be translated or set spinning solely by light. This can test our fundamental understanding: for example does the vacuum exert any friction or drag on the sphere? Do the material properties of the sphere make a difference? Can we use this as a probe to measure pressure in minuscule volumes? What happens when we slow down or cool the random motion of the sphere - can it enter a regime where quantum mechanics dominates? What happens if instead of a sphere we levitate a bacterium? As bacteria can live in 'harsh' environments such work could allow us to start to probe the classical-quantum boundary for biological objects. ii) looking at new ways of imaging with light that could lead us to take images of large biomedical objects (eg tissue, small organs) with "minimal" exposure to light, meaning less damage and faster image acquisition. Can we use "compressive" techniques where we illuminate an object with predetermined light patterns that give us the information of the shape and texture of the object but now with only say 10% of the light we would use normally? We will use this ability to help the world initiative of "mapping the brain" by analyzing the singling of neurons in an intact network.iii) explore new ways to image both the shape and the molecular composition of tissue; such photonics methods can help pathologists identify the early onset of diseases. The same technology, appropriately adapted, may be used to study the shell composition of Antarctic Krill. These marine animals are affected by local environmental temperature and nutrient composition and this is therefore an exciting marker for the impact of climate change. Can our methods be used for imaging other forms of marine life? Can we use shaped light to improve the depth penetration by up to one order of magnitude?iv) can we develop new concepts in the area of sensing? Using simple paper based systems offers promise and can be used in conjunction with shaped light for new forms of multi-parameter sensing, telemedicine.
期刊论文(10)
专著(0)
科研奖励(0)
会议论文
Optical eigenmode description of single-photon light-matter interactions
单光子光与物质相互作用的光学本征模描述
DOI: 10.1117/12.2508394
发表时间: 2019
期刊:
影响因子: --
作者: [Ballantine K]
通讯作者: Ballantine K
Internal physiology of live krill revealed using new aquaria techniques and mixed optical microscopy and optical coherence tomography (OCT) imaging techniques
使用新的水族箱技术以及混合光学显微镜和光学相干断层扫描(OCT)成像技术揭示活磷虾的内部生理学
DOI: 10.1080/10236244.2015.1073455
发表时间: 2015
期刊: Marine and Freshwater Behaviour and Physiology
影响因子: 1
作者: [Cox M]
通讯作者: Cox M
DOI: 10.1021/acsphotonics.5b00178
发表时间: 2015-10-01
期刊: ACS PHOTONICS
影响因子: 7
作者: [Craig, Derek, McDonald, Alison, Dholakia, Kishan]
通讯作者: Dholakia, Kishan
DOI: 10.1038/srep22821
发表时间: 2016-03-15
期刊: Scientific reports
影响因子: 4.6
作者: [Chen M, Dholakia K, Mazilu M]
通讯作者: Mazilu M
6
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    • 项目类别:
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    Challenging the Limits of Photonics:structured light
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    • 财政年份:
      2012
    • 负责人:
      Kishan Dholakia
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      32370914
    • 项目类别:
      面上项目
    • 资助金额:
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    LIGHT促NLRP3炎症小体活化介导他克莫司所致肾纤维化的作用机制研究
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