POSITRON MULTI-DECTECTOR BRAIN ANALYSIS SYSTEM

正电子多探测器脑分析系统

• 批准号: 3504342
• 负责人: HARRY L LOATS
• 金额: $ 5万
• 依托单位: LOATS ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-04-01 至 1989-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3504342
• 关键词: brain imaging /visualization /scanning; brain neoplasms; clinical biomedical equipment; computer program /software; diagnosis quality /standard; image processing; magnetic resonance imaging; mathematical model; neuroanatomy; phantom model; photomultiplier; positron emission tomography

The objective is to develop a new positron multi-detector brain analysis system. The project includes the feasibility demonstration of a computer controlled system to analyze brain tumors using registered images such as MR/CT. A mathematical model incorporating anatomical information from MR is provided to calculate the activity of the tumor. The use of registered MRI/CT images provides a technique for following the course of radiation treatment. This technique is new and innovative since it combines both image mensuration of the size of the tumors as well as their physiologic activity. It provides this capability at approximately 8-10% of the cost of a PET scanner making it a viable supplement or replacement for PET in many types of studies. It has application as a monitoring instrument in the treatment of tumors where it is often necessary to observe tissue condition repeatedly over a long period of time. The system allows reduced radiation exposure (permits up to 200 scans per year versus a limit of 3 per year for PET). The design of the device also significantly reduces the time required to perform a single measurement.

目标是开发一种新的正电子多探测器大脑 分析系统 该项目包括可行性 一个计算机控制的大脑分析系统的演示 使用诸如MR/CT的配准图像来检测肿瘤。 数学模型 结合来自MR的解剖信息， 计算肿瘤的活性。 使用已注册的MRI/CT 图像提供了跟踪辐射过程的技术 治疗 这项技术是新的和创新的，因为它结合了两个图像 测量肿瘤的大小以及它们的生理功能， 活动 它提供的这种能力约为 PET扫描仪的成本使其成为可行的补充， 在许多类型的研究中替代PET。 有应用 作为肿瘤治疗的监测仪器， 经常需要长时间反复观察组织状况 段时间 该系统允许减少辐射暴露 （允许每年最多扫描200次，而对于 PET）。 该装置的设计还大大减少了时间 只需要进行一次测量。