FLYBASE--A DROSOPHILA RELATIONAL DATABASE

这个项目的目标是开发一个果蝇的数据库 将基因组作为科学界的资源。伟大的功利性和 果蝇作为实验系统的特殊优势已经被 反映在它被选为为数不多的人类模式生物之一 基因组计划。关于果蝇遗传和遗传的现有信息 分子生物学已经势不可挡，新的全球研究 像人类基因组办公室支持的那些项目承诺 向社区提供大量新数据。在过去, 数据库已编制为现有的平面文件目录 关于果蝇基因组某些方面的信息。这是……的观点 这一提议，即它现在对于继续开采 以果蝇为模型系统开发一个连续管理的数据库 关于果蝇基因组最重要的信息。在这 多站点协作，我们建议开发一个研究资源， 将满足这一需求。 1.我们将开发一个关系数据库结构，我们将其称为 果蝇基因组的FlyBase。 2.建立持续创新的保管员制度 关于果蝇基因组的信息，以及分配的责任 各种数据表。在四所大学的地点。 3.我们将开发结构、查询系统和前端 从FlyBase检索信息。 4.我们将通过几种方式将FlyBase分发给社区。它 可在线访问、通过CD-ROM或其他电子设备分发 媒体，并偶尔通过硬拷贝摘录 果蝇信息服务(DIS)。

The goal of this project is to develop a database of the Drosophila genome as a resource for the scientific community. The great utility and special advantages of Drosophila as an experimental system has been reflected in its choice as one of the few model organisms for the Human Genome Initiative. The information available on Drosophila genetics and molecular biology is already overwhelming, and new global research projects, such as those supported by the Human Genome Office promise to make huge amounts of new data available to the community. In the past, databases have been prepared as flat file catalogs of existing information on some aspects of the Drosophila genome. It is the view of this proposal that it is now essential to the continued exploitation of Drosophila as a model system to develop a continuously curated database of the most important information on the Drosophila genome. In this multi-site collaboration, we propose to develop a research resource which will meet this need. 1. We will develop a relational database structure, which we will call FlyBase, for the Drosophila genome. 2. We will set up a curatorial system for continuously incorporating new information on the Drosophila genome, with assigned responsibilities for the various data tables. at four university locations. 3. We will develop structures, query systems and front ends for the retrieval of information from FlyBase. 4. We will distribute FlyBase to the community in several fashions. It will be accessible on-line, by distribution by CD-ROM or other electronic media, and by occasional hard copy excerpts comprising issues of the Drosophila Information Service (DIS).