FLYBASE--A DROSOPHILA RELATIONAL DATABASE

这个项目的目标是建立果蝇的数据库 基因组作为科学界的一种资源。 巨大的效用和 果蝇作为一个实验系统的特殊优势一直是 这反映在它被选为人类为数不多的模式生物之一。 基因组计划。 关于果蝇遗传学和 分子生物学已经势不可挡，新的全球研究 人类基因组办公室支持的项目承诺， 向社区提供大量的新数据。 在过去， 数据库已经准备好作为现有的平面文件目录， 果蝇基因组某些方面的信息。 会认为 这一建议，它现在是至关重要的继续利用 果蝇作为一个模型系统，以开发一个持续管理的数据库 果蝇基因组中最重要的信息 在这 多站点协作，我们建议开发一个研究资源， 将满足这一需求。 1.我们将开发一个关系数据库结构，我们称之为 果蝇基因组的FlyBase。 2.我们将建立一个策展系统，不断吸收新的 果蝇基因组的信息，分配的责任， 各种数据表。在四所大学的位置。 3.我们将开发结构，查询系统和前端的 从FlyBase检索信息。 4.我们将以多种方式向社区分发FlyBase。 它 将通过光盘或其他电子方式在网上提供 媒体，并通过偶尔的硬拷贝摘录，包括问题的 Drosophila Information Service（DIS）.

The goal of this project is to develop a database of the Drosophila genome as a resource for the scientific community. The great utility and special advantages of Drosophila as an experimental system has been reflected in its choice as one of the few model organisms for the Human Genome Initiative. The information available on Drosophila genetics and molecular biology is already overwhelming, and new global research projects, such as those supported by the Human Genome Office promise to make huge amounts of new data available to the community. In the past, databases have been prepared as flat file catalogs of existing information on some aspects of the Drosophila genome. It is the view of this proposal that it is now essential to the continued exploitation of Drosophila as a model system to develop a continuously curated database of the most important information on the Drosophila genome. In this multi-site collaboration, we propose to develop a research resource which will meet this need. 1. We will develop a relational database structure, which we will call FlyBase, for the Drosophila genome. 2. We will set up a curatorial system for continuously incorporating new information on the Drosophila genome, with assigned responsibilities for the various data tables. at four university locations. 3. We will develop structures, query systems and front ends for the retrieval of information from FlyBase. 4. We will distribute FlyBase to the community in several fashions. It will be accessible on-line, by distribution by CD-ROM or other electronic media, and by occasional hard copy excerpts comprising issues of the Drosophila Information Service (DIS).