Cytokine Inhibition as a Potential Therapy for ANCA-Associated Glomerulonephritis
Cytokine Inhibition as a Potential Therapy for ANCA-Associated Glomerulonephritis
批准号:
nhmrc : GNT1128267
负责人:
Prof Arthur Kitching
金额:
$92.96万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 --
中文摘要
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英文摘要
MPO-ANCA associated glomerulonephritis is a major cause of renal failure. Current treatments are toxic and poorly effective. Cytokines are immune proteins that direct disease. New biological anti-cytokine treatments are effective but not available for kidney diseases. This study will define the key cytokines driving this disease and provide proof of safety and efficacy in our animal model of this disease. This evidence will allow the introduction of anti-cytokine biologicals in clinical trials.
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Treatments for glomerulonephritis that harness antigen specific regulatory cells
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批准号:nhmrc : 1145105
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项目类别:Project Grants
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资助金额:$41.24万
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财政年份:2018
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负责人:Prof Arthur Kitching
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依托单位:
Conventional and unconventional T cells in interstitial kidney disease
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批准号:nhmrc : GNT1139719
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项目类别:Project Grants
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资助金额:$48.05万
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财政年份:2018
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负责人:Prof Arthur Kitching
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依托单位:
Conventional and unconventional T cells in interstitial kidney disease
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批准号:nhmrc : 1139719
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项目类别:Project Grants
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资助金额:$32.49万
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财政年份:2018
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负责人:Prof Arthur Kitching
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依托单位:
Cytokine Inhibition as a Potential Therapy for ANCA-Associated Glomerulonephritis
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批准号:nhmrc : 1128267
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项目类别:Project Grants
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资助金额:$63.51万
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财政年份:2017
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负责人:Prof Arthur Kitching
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依托单位:
Monocytes on patrol – key mediators of renal injury in glomerulonephritis
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批准号:nhmrc : 1124459
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项目类别:Project Grants
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资助金额:$52.81万
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财政年份:2017
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负责人:Prof Arthur Kitching
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依托单位:
Monocytes on patrol – key mediators of renal injury in glomerulonephritis
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批准号:nhmrc : GNT1124459
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项目类别:Project Grants
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资助金额:$77.29万
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财政年份:2017
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负责人:Prof Arthur Kitching
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依托单位:
RELapses prevENTion in chronic autoimmune disease: common mechanisms and co-morbidities (RELENT)
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批准号:nhmrc : GNT1115805
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项目类别:International Collaborations
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资助金额:$49.98万
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财政年份:2016
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负责人:Prof Arthur Kitching
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依托单位:
The Role of Inflammasomes in Renal Vasculitis
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批准号:nhmrc : GNT1104422
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项目类别:Project Grants
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资助金额:$87.6万
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财政年份:2016
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负责人:Prof Arthur Kitching
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依托单位:
The Role of Inflammasomes in Renal Vasculitis
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批准号:nhmrc : 1104422
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项目类别:Project Grants
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资助金额:$60.27万
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财政年份:2016
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负责人:Prof Arthur Kitching
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依托单位:
RELapses prevENTion in chronic autoimmune disease: common mechanisms and co-morbidities (RELENT)
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批准号:nhmrc : 1115805
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项目类别:Targeted Calls
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资助金额:$34.36万
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财政年份:2016
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负责人:Prof Arthur Kitching
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依托单位:
How the kidney is injured by CD8+ cells in vasculitis
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批准号:nhmrc : GNT1084869
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项目类别:Project Grants
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资助金额:$89.39万
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财政年份:2015
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负责人:Prof Arthur Kitching
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依托单位:
How the kidney is injured by CD8+ cells in vasculitis
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批准号:nhmrc : 1084869
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项目类别:Project Grants
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资助金额:$61.93万
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财政年份:2015
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负责人:Prof Arthur Kitching
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依托单位:
Imaging neutrophil and endothelial function in acute glomerulonephritis
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批准号:nhmrc : 1064112
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项目类别:Project Grants
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资助金额:$36.38万
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财政年份:2014
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负责人:Prof Arthur Kitching
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依托单位:
Intravascular Immunity in Glomerulonephritis
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批准号:nhmrc : 1045165
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项目类别:Project Grants
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资助金额:$39.08万
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财政年份:2013
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负责人:Prof Arthur Kitching
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依托单位:
Mechanisms of infection triggered renal vasculitis
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批准号:nhmrc : 1008849
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项目类别:NHMRC Project Grants
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资助金额:$27.6万
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财政年份:2011
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负责人:Prof Arthur Kitching
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依托单位:
Mechanisms of Th17 induced injury in the kidney
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批准号:nhmrc : 1010563
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项目类别:Project Grants
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资助金额:$31.71万
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财政年份:2011
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负责人:Prof Arthur Kitching
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依托单位:
Immunoregulation in the Pathogenesis and Therapy of Autoimmune anti Myeloperoxidase Glomerulonephritis
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批准号:nhmrc : 606684
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项目类别:NHMRC Project Grants
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资助金额:$18.93万
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财政年份:2010
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负责人:Prof Arthur Kitching
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依托单位:
Mechanisms of Disease in Humans with MPO-ANCA Associated Glomerulonephritis
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批准号:nhmrc : 606683
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项目类别:NHMRC Project Grants
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资助金额:$35.58万
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财政年份:2010
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负责人:Prof Arthur Kitching
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依托单位:
Mechanisms of Glomerular Leukocyte Recruitment
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批准号:nhmrc : 606564
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项目类别:NHMRC Project Grants
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资助金额:$39.1万
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财政年份:2010
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负责人:Prof Arthur Kitching
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依托单位:
The role of renal dendritic cells in infection and immunity under immunosuppression
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批准号:nhmrc : 565033
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项目类别:NHMRC Project Grants
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资助金额:$31.68万
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财政年份:2009
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负责人:Prof Arthur Kitching
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依托单位:
海外基金