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Cytokine Inhibition as a Potential Therapy for ANCA-Associated Glomerulonephritis

Cytokine Inhibition as a Potential Therapy for ANCA-Associated Glomerulonephritis
细胞因子抑制作为 ANCA 相关肾小球肾炎的潜在疗法
批准号:
nhmrc : GNT1128267
负责人:
Prof Arthur Kitching
金额:
$92.96万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 --

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中文摘要
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英文摘要
MPO-ANCA associated glomerulonephritis is a major cause of renal failure. Current treatments are toxic and poorly effective. Cytokines are immune proteins that direct disease. New biological anti-cytokine treatments are effective but not available for kidney diseases. This study will define the key cytokines driving this disease and provide proof of safety and efficacy in our animal model of this disease. This evidence will allow the introduction of anti-cytokine biologicals in clinical trials.
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Treatments for glomerulonephritis that harness antigen specific regulatory cells
  • 批准号:
    nhmrc : 1145105
  • 项目类别:
    Project Grants
  • 资助金额:
    $41.24万
  • 财政年份:
    2018
  • 负责人:
    Prof Arthur Kitching
  • 依托单位:
Conventional and unconventional T cells in interstitial kidney disease
  • 批准号:
    nhmrc : GNT1139719
  • 项目类别:
    Project Grants
  • 资助金额:
    $48.05万
  • 财政年份:
    2018
  • 负责人:
    Prof Arthur Kitching
  • 依托单位:
Conventional and unconventional T cells in interstitial kidney disease
  • 批准号:
    nhmrc : 1139719
  • 项目类别:
    Project Grants
  • 资助金额:
    $32.49万
  • 财政年份:
    2018
  • 负责人:
    Prof Arthur Kitching
  • 依托单位:
Cytokine Inhibition as a Potential Therapy for ANCA-Associated Glomerulonephritis
  • 批准号:
    nhmrc : 1128267
  • 项目类别:
    Project Grants
  • 资助金额:
    $63.51万
  • 财政年份:
    2017
  • 负责人:
    Prof Arthur Kitching
  • 依托单位:
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