Conventional and unconventional T cells in interstitial kidney disease

间质性肾病中的常规和非常规 T 细胞

• 批准号: nhmrc : 1139719
• 负责人: Prof Arthur Kitching
• 金额: $ 32.49万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/conventional-unconventional-t-kidney-disease/1319068
• 关键词: Conventional; unconventional; cells; interstitial; kidney

Acute damage to the kidney is a common life-threatening condition. Recent studies have shown that less well-studied types of immune cells contribute to kidney damage. However, how these cells enter and injure the kidney is unknown. In this project we will use a special microscope to look into the blood vessels of the kidney and visualise the cells inside kidney blood vessels in order to uncover their behaviour as they respond to acute inflammatory insult to the kidney.

肾脏的急性损伤是一种常见的危及生命的疾病。最近的研究表明，研究较少的免疫细胞类型会导致肾脏损伤。然而，这些细胞是如何进入并损害肾脏的尚不清楚。在这个项目中，我们将使用一种特殊的显微镜来观察肾脏的血管，并可视化肾脏血管内的细胞，以揭示它们在对肾脏的急性炎症性侮辱做出反应时的行为。