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Immunoregulation in the Pathogenesis and Therapy of Autoimmune anti Myeloperoxidase Glomerulonephritis

Immunoregulation in the Pathogenesis and Therapy of Autoimmune anti Myeloperoxidase Glomerulonephritis
自身免疫性抗髓过氧化物酶肾小球肾炎发病机制及治疗中的免疫调节
批准号:
nhmrc : 606684
负责人:
Prof Arthur Kitching
金额:
$18.93万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31

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中文摘要
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英文摘要
Glomerulonephritis (GN) is a major health burden and crescentic GN is the most severe form. Most patients have autoantibodies to their own white blood cell ANCA, causing the disease. This study will use a mouse model of ANCA associated autoimmunity causing crescentic GN to define the normal mechanisms preventing the development of this disease (immunoregulation) and test the potential of new cell based therapies to prevent and treat the disease.
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Treatments for glomerulonephritis that harness antigen specific regulatory cells
  • 批准号:
    nhmrc : 1145105
  • 项目类别:
    Project Grants
  • 资助金额:
    $41.24万
  • 财政年份:
    2018
  • 负责人:
    Prof Arthur Kitching
  • 依托单位:
Conventional and unconventional T cells in interstitial kidney disease
  • 批准号:
    nhmrc : GNT1139719
  • 项目类别:
    Project Grants
  • 资助金额:
    $48.05万
  • 财政年份:
    2018
  • 负责人:
    Prof Arthur Kitching
  • 依托单位:
Conventional and unconventional T cells in interstitial kidney disease
  • 批准号:
    nhmrc : 1139719
  • 项目类别:
    Project Grants
  • 资助金额:
    $32.49万
  • 财政年份:
    2018
  • 负责人:
    Prof Arthur Kitching
  • 依托单位:
Cytokine Inhibition as a Potential Therapy for ANCA-Associated Glomerulonephritis
  • 批准号:
    nhmrc : 1128267
  • 项目类别:
    Project Grants
  • 资助金额:
    $63.51万
  • 财政年份:
    2017
  • 负责人:
    Prof Arthur Kitching
  • 依托单位:
海外基金