课题基金 / 基金详情

DEVELOPMENT OF MICROCALORIMETERS FOR THE STUDY OF BIOLOGICAL REACTIONS

DEVELOPMENT OF MICROCALORIMETERS FOR THE STUDY OF BIOLOGICAL REACTIONS
用于生物反应研究的微热量计的开发
批准号：
3858013
负责人：
R L BERGER
金额：
$0.0万
依托单位：
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3858013
关键词：
bioengineering /biomedical engineering biomedical equipment development chemical binding chemical reaction endotoxins heat hemoglobin ionic bond ligands lipopolysaccharides mathematics microcalorimetry reagent /indicator thermodynamics

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中文摘要
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英文摘要
The tantalum stopped-flow microcalorimeter has been utilized this year in the initiating of studies of isoionic binding studies, both of ligand and effector molecules, and for the study of the study of the binding of endotoxin (lipid polysaccharide to hemoglobin. Various improvements in the ease of operation of the calorimeter and to its versatility have been initiated as a result of suggestions from several researchers using the instrument. The new pulsed heat capacity calorimeter has been improved considerably and the mathematics worked out for the simultaneous measurement of both the heat capacity and thermal conduction of a liquid sample.
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DEVELOPMENT OF BIOPHYSICAL METHODS FOR STUDYING BIOCHEMICAL REACTIONS
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DEVELOPMENT OF BIOCALORIMETERS FOR SOLUTION AND CELL BIOCHEMICAL STUDIES