POST-ISCHEMIC ACCUMULATION OF CALCIUM IN BRAIN TISSUE

钙的分布和时间序列的观测 单次和重复脑缺血损伤后的蓄积 45钙放射自显影显示模式有显著差异 单次闭塞和重复闭塞之间钙摄取的差异。惊人的一击 反复缺血时钙蓄积的特点是强烈摄取 Ca++在丘脑、纹状体，后来在内侧膝状体和 黑质。此外，一个令人震惊的发现是中国人对钙离子的强烈吸收 当锥体神经元几乎被破坏时，CAL。我们的观察 提示钙的异常积聚可能是由其他原因引起的 而不是直接的缺血性损伤，并不一定表明 不可逆转的神经元损伤。

Observations on the distribution and the time sequences of calcium accumulation following single and repetitive ischemic insults using 45calcium autoradiography revealed significant differences in the pattern of calcium uptake between single and repeated occlusions. A striking feature of calcium accumulation in repeated ischemia was intense uptake of Ca + + in thalamus, striatum and, later, in the medial geniculate and substantia nigra. Also, a striking finding was an intense Ca + + uptake in CAl when the pyramidal neurons were virtually destroyed. Our observations suggest that abnormal accumulation of calcium may be due to other causes than a direct ischemic injury and may not necessarily indicate irreversible neuronal damage.