HIGH SPEED DIFFERENTIAL STOPPED FLOW CALORIMETER

本文介绍了一种单通道、高速、停流式量热计 用于评估混合速度、流速、压降， 热探测灵敏度该系统采用变速飞轮 以及电致动离合器，以将足够的能量传递到两个 驱动注射器在5毫秒内混合200微升的试剂体积 来自驱动注射器的入口管以及混合器和 检测室保持在25 - 50 ℃恒温 ℃的超快热敏电阻（1 ms）位于检测室中 以测量反应期间的温度上升。一个新的驱动凸轮， 所使用的注射器产生恒定的加速度。混合 腔室包含一个石英观察管，以允许光学测量 反应。观察管在O形密封圈中“浮动”以减少冲击 混合过程中的负载。

A preliminary single channel, high speed, stopped-flow calorimeter has been constructed to evaluate mixing speeds, flow velocities, pressure drops, and thermal detection sensitivity. The system uses a variable speed flywheel and electrically actuated clutch to transfer sufficient energy to the two drive syringes to mix reagent volumes of 200 microliters in 5 milliseconds or less. The inlet tubes from the drive syringes, as well as the mixer and the detection chamber are kept at constant temperature between 25 and 50 deg C. An ultra-fast thermistor (I ms) is located in the detection chamber to measure the temperature rise during the reaction. A new drive cam is used which produces a constant acceleration of the syringes. The mixing chamber contains a quartz observation tube to allow optical measurement of the reaction. The observation tube 'floats' in o-ring seals to reduce shock loads during mixing.