HIGH SPEED DIFFERENTIAL STOPPED FLOW CALORIMETER

高速差示停流热量计

• 批准号: 3937344
• 负责人: C P MUDD
• 金额: --
• 依托单位: DIVISION OF RESEARCH SERVICES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3937344
• 关键词: biomedical device power system; calorimetry; nonblood rheology; optics; stop flow technique; thermodynamics

A preliminary single channel, high speed, stopped-flow calorimeter has been constructed to evaluate mixing speeds, flow velocities, pressure drops, and thermal detection sensitivity. The system uses a variable speed flywheel and electrically actuated clutch to transfer sufficient energy to the two drive syringes to mix reagent volumes of 200 microliters in 10 milliseconds or less. The inlet tubes from the drive syringes, as well as the mixer and the detection chamber are kept at constant temperature between 25 and 50 deg C. An ultra-fast thermistor (1 ms) is located in the detection chamber to measure the temperature rise during the reaction. The detection chamber also contains a quartz observation tube for optical measurement of the reaction.

单通道高速停流式量热计的初步研究 已经被构造来评估混合速度，流速， 压降和热检测灵敏度。 该系统使用 变速飞轮和电致动离合器， 将足够的能量转移到两个驱动注射器以混合试剂 在10毫秒或更短的时间内完成200微升的体积。 驱动注射器的管，以及混合器和 检测室保持在25 ℃和25 ℃之间的恒定温度下， 50 ℃的 超快热敏电阻（1 ms）位于 检测室，以测量在加热期间的温度上升。 反应 检测室还包含一个石英观察装置 反应的光学测量管。