DEFINING SUBPOPULATIONS OF PATHOGENIC MACROPHAGES UNDERLYING LUNG DISEASES
DEFINING SUBPOPULATIONS OF PATHOGENIC MACROPHAGES UNDERLYING LUNG DISEASES
批准号:
nhmrc : 1008298
负责人:
A/Pr Margaret Hibbs
金额:
$42.71万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31
中文摘要
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英文摘要
Chronic obstructive pulmonary disease (COPD) is a serious lung disease that afflicts over 1 million people in Australia and adenocarcinoma is a common fatal lung cancer; both are typically caused by cigarette smoking, and macrophage-rich inflammation is a hallmark feature. Macrophages can destroy lung tissue and promote cancer development. Herein we will identify and profile macrophage subpopulations that are associated with lung inflammation and cancer to identify therapeutic targets that may yield novel intervention strategies.
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会议论文
G-CSF: a pathogenic effector in chronic obstructive pulmonary disease and its comorbidities
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批准号:nhmrc : 1141208
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项目类别:Project Grants
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资助金额:$83.95万
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财政年份:2018
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负责人:A/Pr Margaret Hibbs
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依托单位:
G-CSF: a pathogenic effector in chronic obstructive pulmonary disease and its comorbidities
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批准号:nhmrc : GNT1141208
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项目类别:Project Grants
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资助金额:$124.16万
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财政年份:2018
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负责人:A/Pr Margaret Hibbs
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依托单位:
Dissecting the contribution of IL-17-producing γδ T cells in the pathogenesis of airway diseases
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批准号:nhmrc : GNT1147267
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项目类别:Project Grants
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资助金额:$72.44万
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财政年份:2018
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负责人:A/Pr Margaret Hibbs
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依托单位:
Dissecting the contribution of IL-17-producing ?? T cells in the pathogenesis of airway diseases
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批准号:nhmrc : 1147267
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项目类别:Project Grants
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资助金额:$48.98万
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财政年份:2018
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负责人:A/Pr Margaret Hibbs
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依托单位:
Characterisation of emerging new signaling networks that underlie COPD phenotypes
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批准号:nhmrc : 1100099
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项目类别:Project Grants
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资助金额:$47.79万
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财政年份:2016
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负责人:A/Pr Margaret Hibbs
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依托单位:
Characterisation of emerging new signaling networks that underlie COPD phenotypes
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批准号:nhmrc : GNT1100099
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项目类别:Project Grants
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资助金额:$69.7万
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财政年份:2016
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负责人:A/Pr Margaret Hibbs
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依托单位:
Targeting macrophage subtypes as a strategy for chronic inflammatory lung disease therapy
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批准号:nhmrc : 1080274
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项目类别:Project Grants
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资助金额:$44.04万
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财政年份:2015
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负责人:A/Pr Margaret Hibbs
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依托单位:
Defining the cellular and molecular mechanisms underlying autoimmunity using a model of SLE
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批准号:nhmrc : 1008288
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项目类别:NHMRC Project Grants
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资助金额:$41.67万
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财政年份:2011
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负责人:A/Pr Margaret Hibbs
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依托单位:
Research Fellowship
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批准号:nhmrc : 603124
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项目类别:NHMRC Research Fellowships
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资助金额:$47.72万
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财政年份:2010
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负责人:A/Pr Margaret Hibbs
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依托单位:
Lyn tyrosine kinase sgnalling cascades
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批准号:nhmrc : 513714
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项目类别:NHMRC Project Grants
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资助金额:$52.18万
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财政年份:2008
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负责人:A/Pr Margaret Hibbs
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依托单位:
The role of Src family tyrosine kinases in inflammatory lung disease and cancer
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批准号:nhmrc : 487910
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项目类别:NHMRC Project Grants
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资助金额:$35.7万
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财政年份:2008
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负责人:A/Pr Margaret Hibbs
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依托单位:
Src family kinases: regulation of phosphoinositol-3 kinase signaling and autoimmune disease development.
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批准号:nhmrc : 433622
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项目类别:NHMRC Project Grants
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资助金额:$35.12万
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财政年份:2007
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负责人:A/Pr Margaret Hibbs
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依托单位:
Tumour suppressor networks: the role of SHIP-1 and Lyn in suppressing haematopoietic tumours
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批准号:nhmrc : 381402
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项目类别:NHMRC Project Grants
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资助金额:$31.31万
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财政年份:2006
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负责人:A/Pr Margaret Hibbs
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 280905
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项目类别:NHMRC Research Fellowships
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资助金额:$42.64万
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财政年份:2004
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负责人:A/Pr Margaret Hibbs
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依托单位:
An analysis of the Lyn tyrosine kinase in the regulation of hematopoiesis and tumourigenesis.
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批准号:nhmrc : 280902
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项目类别:NHMRC Project Grants
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资助金额:$25.41万
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财政年份:2004
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负责人:A/Pr Margaret Hibbs
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依托单位:
Is Lyn tyrosine kinase a predictor of severe, persistent multi-trait asthma and allergy?
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批准号:nhmrc : 234705
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项目类别:NHMRC Project Grants
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资助金额:$16.69万
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财政年份:2003
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负责人:A/Pr Margaret Hibbs
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依托单位:
Dissecting the role of the Lyn tyrosine kinase in B cell differentiation and the development of autoimmunity.
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批准号:nhmrc : 234704
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项目类别:NHMRC Project Grants
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资助金额:$32.51万
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财政年份:2003
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负责人:A/Pr Margaret Hibbs
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依托单位:
海外基金