Characterisation of emerging new signaling networks that underlie COPD phenotypes

COPD 表型背后新兴信号网络的表征

• 批准号: nhmrc : 1100099
• 负责人: A/Pr Margaret Hibbs
• 金额: $ 47.79万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/characterisation-emerging-new-copd-phenotypes/662493
• 关键词: Characterisation; emerging; new; signaling; networks

Incurable diseases such as chronic obstructive pulmonary disease are becoming increasingly prevalent in Australia’s aging population and new therapies are urgently needed. We have discovered a possible cause of severe emphysema and developed a novel method to image functional changes in the diseased lung. Using advanced molecular and imaging techniques we are now probing for ways to turn this discovery into effective treatments for this fatal disease.

慢性阻塞性肺病等无法治愈的疾病在澳大利亚老龄化人口中越来越普遍，迫切需要新的治疗方法。我们已经发现了严重肺气肿的可能原因，并开发了一种新的方法来成像病变肺的功能变化。利用先进的分子和成像技术，我们正在探索如何将这一发现转化为这种致命疾病的有效治疗方法。