GAS & LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY SYSTEM

现代质谱仪与气相色谱和质谱联用 液相色谱入口和化学电离能力 将在化学科学学院进行日常使用 质谱实验室支持教师的研究， 博士后，研究生在化学和 生物化学。 这个仪器将取代一个16岁的 光谱仪 GC/LC/CIMS系统的主要用户将是P. Beak、R. M.科茨， S. E.丹麦，J. A. Katzenellenbogen，K. L. Rinehart，G. B。 Schuster，K. S. Suslick，S. C. Zimmermann和S. G. Sligar在 他们对萜烯、甾醇和抗生素生物合成的研究， 合成;金属酶，由它们形成的产物， 合成类似物; DNA双嵌入剂;氟标记类固醇 和取代的雌激素;抗生素的结构，海洋 天然产物和昆虫神经肽;光化学产物 从有机硼化合物;新的合成中间体 （有机金属和手性试剂，氘标记）。 其他用户为N。伦纳德，E. Oldfield，D. N. Hendrickson，W. G. Klemperer，T. B。劳赫富斯角A.布罗卡岛C. 贡萨卢斯湖P. Hager和R. S.沃尔夫，他们将雇用 GC/LC/CIMS系统在核酸类似物、细胞色素 裂解肽，产甲烷菌辅酶，金属蛋白， 卤化酶，磷脂，糖脂， 鞘糖脂，过渡金属硫化物簇，低 高温陶瓷及船用合成中间体 天然产物和萜烯。

A modern mass spectrometer with coupled gas chromatography and liquid chromatography inlets and chemical ionization capability will be employed for routine use in the School of Chemical Sciences Mass Spectrometry Laboratory to support the research of faculty, postdoctorates, and graduate students in Chemistry and Biochemistry. This instrument will replace a 16-year-old spectrometer. Major users of the GC/LC/CIMS system will be P. Beak, R. M. Coates, S. E. Denmark, J. A. Katzenellenbogen, K. L. Rinehart, G. B. Schuster, K. S. Suslick, S. C. Zimmermann, and S. G. Sligar in their studies of terpene, sterol, and antibiotic biosynthesis and synthesis; metalloenzymes, products formed by them, and their synthetic analogs; DNA bis-intercalators; fluorine-labeled steroids and substituted estrogens; structures of antibiotics, marine natural products and insect neuropeptides; photochemical products from organoboron compounds; novel synthetic intermediates (organometallic and chiral reagents, deuterium labeled). Additional users will be N. J. Leonard, E. Oldfield, D. N. Hendrickson, W. G. Klemperer, T. B. Rauchfuss, C. A. Broka, I. C. Gunsalus, L. P. Hager, and R. S. Wolfe, and they will employ the GC/LC/CIMS system in studies of nucleic acid analogues, cytochrome cleavage peptides, methanogen coenzymes, metalloproteins, halogenating enzymes, phospholipids, glycolipids, glycosphingolipids, transition metal sulfide clusters, low temperature ceramics, and synthetic intermediates for marine natural products and terpenes.