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GAS & LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY SYSTEM

气体

基本信息

批准号：
3520135
负责人：
JIRI JONAS
金额：
$ 40万
依托单位：
UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
依托单位国家：
美国
项目类别：
财政年份：
1989
资助国家：
美国
起止时间：
1989-07-06 至 1990-07-05
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/3520135
关键词：
biomedical equipment purchase gas chromatography mass spectrometry

项目摘要

A modern mass spectrometer with coupled gas chromatography and liquid chromatography inlets and chemical ionization capability will be employed for routine use in the School of Chemical Sciences Mass Spectrometry Laboratory to support the research of faculty, postdoctorates, and graduate students in Chemistry and Biochemistry. This instrument will replace a 16-year-old spectrometer. Major users of the GC/LC/CIMS system will be P. Beak, R. M. Coates, S. E. Denmark, J. A. Katzenellenbogen, K. L. Rinehart, G. B. Schuster, K. S. Suslick, S. C. Zimmermann, and S. G. Sligar in their studies of terpene, sterol, and antibiotic biosynthesis and synthesis; metalloenzymes, products formed by them, and their synthetic analogs; DNA bis-intercalators; fluorine-labeled steroids and substituted estrogens; structures of antibiotics, marine natural products and insect neuropeptides; photochemical products from organoboron compounds; novel synthetic intermediates (organometallic and chiral reagents, deuterium labeled). Additional users will be N. J. Leonard, E. Oldfield, D. N. Hendrickson, W. G. Klemperer, T. B. Rauchfuss, C. A. Broka, I. C. Gunsalus, L. P. Hager, and R. S. Wolfe, and they will employ the GC/LC/CIMS system in studies of nucleic acid analogues, cytochrome cleavage peptides, methanogen coenzymes, metalloproteins, halogenating enzymes, phospholipids, glycolipids, glycosphingolipids, transition metal sulfide clusters, low temperature ceramics, and synthetic intermediates for marine natural products and terpenes.

现代质谱联用气相色谱和

项目成果

期刊论文数量（15）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Rh(2)(II)-catalyzed synthesis of carbazoles from biaryl azides.

DOI：
10.1021/jo9002536
发表时间：
2009-04-17
期刊：
The Journal of organic chemistry
影响因子：
0
作者：
Stokes BJ;Jovanović B;Dong H;Richert KJ;Riell RD;Driver TG
通讯作者：
Driver TG

Anticancer (hexacarbonyldicobalt)propargyl aryl ethers: synthesis, antiproliferative activity, apoptosis induction, and effect on cellular oxidative stress.

DOI：
10.1016/j.jinorgbio.2012.10.014
发表时间：
2013-02
期刊：
Journal of inorganic biochemistry
影响因子：
3.9
作者：
Sydonie D Schimler;D. Hall;Stefan L. Debbert
通讯作者：
Sydonie D Schimler;D. Hall;Stefan L. Debbert

Examination of the mechanism of Rh(2)(II)-catalyzed carbazole formation using intramolecular competition experiments.

DOI：
10.1021/jo901224k
发表时间：
2009-09-04
期刊：
The Journal of organic chemistry
影响因子：
0
作者：
Stokes BJ;Richert KJ;Driver TG
通讯作者：
Driver TG

Synthetic tuning of electronic and photophysical properties of 2-aryl-1,3-benzothiaphospholes.

2-芳基-1,3-苯并硫杂磷的电子和光物理性质的综合调节。

DOI：
10.1021/jo400947u
发表时间：
2013
期刊：
The Journal of organic chemistry
影响因子：
0
作者：
Worch,JoshuaC;Chirdon,DanielleN;Maurer,AndrewB;Qiu,Yunyan;Geib,StevenJ;Bernhard,Stefan;Noonan,KevinJT
通讯作者：
Noonan,KevinJT

Vicianin, prunasin, and beta-cyanoalanine in common vetch seed as sources of urinary thiocyanate in the rat.

野豌豆种子中的豌豆素、普鲁那辛和β-氰基丙氨酸是大鼠尿硫氰酸盐的来源。