FLUORIDE MOUTHRINSING AND FLUORIDE TABLETS USED SEPARATELY AND IN COMBINATION

氟化物漱口剂和氟化物片剂单独和组合使用

• 批准号: 3939945
• 负责人: S B HEIFETZ
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3939945
• 关键词: dental caries inhibitor; dosage forms; human subject; human therapy evaluation; ingested fluoride therapy; mouthwash; preschool child (1-5); preventive dentistry; topical fluoride therapy

In September 1981, a self-administered dental program was begun in Springfield, Ohio, a fluoride-deficient community. The approximately 1700 children attending 20 public and non-public elementary schools were randomly assigned to one of three treatment groups. The children in Group I dissolve and ingest daily a 1 mg F tablet; the children in Group III rinse weekly with a 0.2% NaF solution; and Group II carries out both procedures. The assigned treatments are self-administered under the supervision of the teacher. Before the procedures were started, baseline examinations were conducted. First and second follow-up dental examinations were conducted in October 1983 and November 1986 respectively. The procedures will be continued through 1989 and followed by a clinical examination. Three to four years following the cessation of treatments, a post-treatment examination will be conducted in high school to determine the extent of continued protection. Supplies have been ordered, schedules arranged and local personnel identified for the start of the seventh school year of treatments in October 1987.

1981年9月，一个自我管理的牙科项目开始了