FLUORIDE MOUTHRINSING AND FLUORIDE TABLETS USED SEPARATELY AND IN COMBINATION

氟化物漱口剂和氟化物片剂单独和组合使用

• 批准号: 3963719
• 负责人: S B HEIFETZ
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3963719
• 关键词: dental caries inhibitor; dosage forms; human subject; human therapy evaluation; ingested fluoride therapy; mouthwash; preschool child (1-5); preventive dentistry; topical fluoride therapy

Approximately 1700 kindergarten and first grade children were randomly assigned to one of the following groups: Group I - Rinses once every week in school with a 0.2% fluoride solution. Group III - Ingests once a day in school a sodium fluoride tablet containing 1 mg of fluoride. Group II - Carries out the regimens for both Group I and Group III. The method of assignment resulted in three comparable groups, each containing about 560 children. Participants carry out their assigned treatments in classrooms under the supervision of a teacher. Treatments will be administered for a minimum of eight years. Baseline dental examinations were conducted in September 1981. The prescribed treatments were initiated shortly after the examinations were completed. In September 1985, the fifth school year of treatments began in the classrooms. First follow-up dental examinations were made in October 1983 of 1,154 participants who were then in grades 2 and 3. Supplies have been ordered, schedules arranged and local personnel identified for the start-up of the sixth school year of treatments in September 1986.

大约1700名幼儿园和一年级的儿童被随机 分配到以下组之一： 第一组：每周在学校用0.2%的氟化物溶液冲洗一次。 第三组-在学校每天摄入一片氟化钠 含有1毫克的氟化物。 第二组-执行第一组和第三组的方案。 分配方法产生了三个可比较的组，每个组 约560名儿童。 参与者执行他们的分配 在老师的监督下在教室里进行治疗。 治疗 将被执行至少八年 基线牙科 1981年9月进行了检查。 处方治疗 在考试结束后不久就开始了。 1985年9月，第五个学年的治疗开始了， 教室 1983年10月进行了第一次后续牙科检查 1，154名参与者当时在2年级和3年级。 物资已 订购、安排时间表和确定启动的当地人员 1986年9月，第六学年的治疗。