OPTICAL METHODS FOR THE NONDESTRUCTIVE EVALUATION OF COLLAGEN IN HEART VALVES

心脏瓣膜中胶原蛋白无损评估的光学方法

• 批准号: 3942917
• 负责人: V J FERRANS
• 金额: --
• 依托单位: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3942917
• 关键词: birefringences; heart valve transplantation; heart valves; imaging /visualization /scanning

An assessment was made of the suitability of optical methods as means of nondestructively evaluating the morphology of collagen in intact leaflets of bioprosthetic valves. The results demonstrate that transmitted polarized light and incident polarized light optics facilitate the imaging of the inherent birefringence of valvular collagen fibers and serve to determine the patterns of collagen configuration and orientation in unimplanted and explanted porcine aortic valvular and bovine pericardial bioprostheses.

对光学方法的适用性进行了评估 无损评估胶原形态的方法 在完整的生物瓣膜小叶中。 结果表明 透射偏振光和入射偏振光光学器件 促进瓣膜固有双折射的成像 胶原纤维并用于确定胶原蛋白的模式 未植入和外植的配置和方向 猪主动脉瓣膜和牛心包生物假体。