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ENDOTHELIAL FENESTRATIONS OF THE ALVEOLAR CAPILLARIES IN FIBROTIC LUNG DISORDERS

ENDOTHELIAL FENESTRATIONS OF THE ALVEOLAR CAPILLARIES IN FIBROTIC LUNG DISORDERS
纤维化肺疾病中肺泡毛细血管的内皮开窗
批准号：
3843448
负责人：
V J FERRANS
金额：
$0.0万
依托单位：
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3843448
关键词：
biopsy capillary electron microscopy histopathology human tissue lung alveolus metaplasia phenotype pulmonary fibrosis /granuloma respiratory epithelium vascular endothelium permeability

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中文摘要
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英文摘要
Electron microscopic studies of lung biopsy specimens reveal the presence of pulmonary alveolar capillaries of the fenestrated type (containing diaphragm-like openings or fenestrae in their cytoplasm) in 20 of 28 patients with a variety of fibrotic lung disorders. Such capillaries are normally present in bronchial mucosa, but not in alveoli. Consideration is given to the possibility that this phenotypic change represents a metaplastic process analogous to that which occurs in pulmonary alveolar epithelium in fibrotic lung disorders.
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会议论文
Characterization of alpha 2-adrenergic receptor subtype-specific antibodies.
α2-肾上腺素能受体亚型特异性抗体的表征。
DOI： --
发表时间： 1993
期刊： Molecular pharmacology
影响因子： 3.6
作者： [Kurose,H, Arriza,JL, Lefkowitz,RJ]
通讯作者： Lefkowitz,RJ
STUDIES OF THE MORPHOLOGY OF THE BIOPROSTHETIC HEART VALVES
SURGICAL PATHOLOGY OF THE CARDIOVASCULAR SYSTEM
ULTRASTRUCTURE AND FUNCTION OF THE MYOCARDIUM--AN OVERVIEW
INTRALUMINAL FIBROSIS IN FIBROTIC LUNG DISORDERS
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