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EVALUATION OF ACUTE AND CHRONIC CARDIOTOXICITY IN MINIATURE SWINE

EVALUATION OF ACUTE AND CHRONIC CARDIOTOXICITY IN MINIATURE SWINE
小型猪急性和慢性心脏毒性的评价
批准号：
3942924
负责人：
V J FERRANS
金额：
$0.0万
依托单位：
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3942924
关键词：
cardiotoxin disease /disorder model doxorubicin drug screening /evaluation minoxidil

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中文摘要
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英文摘要
An evaluation was made of the suitability of miniature swine as animal models for the morphologic assessment of changes related to the acute and the chronic cardiotoxicity produced by pharmacologic agents. Minoxidil and doxorubicin were used as experimental agents capable of producing acute and chronic cardiotoxicity, respectively. The results obtained show that miniature swine are useful models to study both types of cardiotoxicity.
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会议论文
STUDIES OF THE MORPHOLOGY OF THE BIOPROSTHETIC HEART VALVES
SURGICAL PATHOLOGY OF THE CARDIOVASCULAR SYSTEM
ULTRASTRUCTURE AND FUNCTION OF THE MYOCARDIUM--AN OVERVIEW
INTRALUMINAL FIBROSIS IN FIBROTIC LUNG DISORDERS