MECHANICAL PROSTHETIC HEART VALVE TESTER

机械人工心脏瓣膜测试仪

• 批准号: 3959976
• 负责人: T L TALBOT
• 金额: --
• 依托单位: DIVISION OF RESEARCH SERVICES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3959976
• 关键词: aortic valve; bioengineering /biomedical engineering; blood pressure; mechanical pressure; noninvasive diagnosis; prosthetic heart valve; ultrasound blood flow measurement

Six different manufactures' prosthetic heart valves were tested and ranked according to performance indices described by W. Swanson and S. Gabby. Additionally, a technique was devised whereby the pressure drop across the aortic valve could be predicted by velocity measurements made with continuous wave Doppler (CWD) imaging. The results of preliminary in vitro studies demonstrate a high correlation (r greater than 0.9) between the peak velocity as measured with CWD and the predicted velocity obtained by the application of a simplified Bernoulli equation, which uses a measured maximum pressure drop across the aortic valve. Also, an acoustical signature analysis technique is under investigation for possible non- invasive detection of partially-failed single leaflet type mechanical valves.

测试了六种不同制造商的人造心脏瓣膜