MECHANICAL PROSTHETIC HEART VALVE TESTER

机械人工心脏瓣膜测试仪

• 批准号: 5204054
• 负责人: T L TALBOT
• 金额: --
• 依托单位: NATIONAL CENTER FOR RESEARCH RESOURCES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5204054
• 关键词: aortic valve; biomedical equipment development; diagnosis design /evaluation; heart disorder diagnosis; heart valve disorder; intracardiac pressure; noninvasive diagnosis; prosthetic heart valve; ultrasound blood flow measurement

Six different manufacturers' prosthetic heart valves were tested and ranked according to the performance indices described by Swanson and Gabbay. Additionally, a technique was devised whereby the pressure drop across the aortic valve could be predicted by velocity measurements made with continuous-wave Doppler (CWD) imaging. The results of preliminary in vitro studies demonstrate a high correlation (r>0.9) between the peak velocity as measured with CWD and the predicted velocity obtained by the application of a simplified Bernoulli equation, which uses a measured maximum pressure drop across the aortic valve. Also, an acoustical signature analysis technique is under investigation for possible noninvasive detection of partially failed single-leaflet-type mechanical valves.

测试了六个不同制造商的人造心脏瓣膜