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PERIPHERAL AND CENTRAL CATECHOLAMINES IN HYPERTENSION AND STRESS

PERIPHERAL AND CENTRAL CATECHOLAMINES IN HYPERTENSION AND STRESS
外周和中枢儿茶酚胺在高血压和压力中的作用
批准号:
3968434
负责人:
J M SAAVEDRA
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
我们研究了外周和中枢儿茶酚胺的作用, 血管紧张素II在心血管功能的调节。 我们确定了含有肾上腺素神经元的特定大脑区域 控制儿茶酚胺和加压素的释放, 血压和心率 我们确定了中后叶的确切来源 脑垂体儿茶酚胺 β-肾上腺素能受体与动脉粥样硬化之间存在密切的相互作用, 血管紧张素转换酶 脑血管紧张素系统,无论是在转换酶和 受体水平,参与心血管控制的自发性 高血压大鼠
英文摘要
We studied the role of peripheral and central catecholamines and angiotensin II in the regulation of cardiovascular function. We established that specific brain areas containing adrenaline neurons control both catecholamine and vasopressin release and influence blood pressure and heart rate. We determined the precise source of intermediate and posterior lobe pituitary catecholamines. There are close interactions between beta-adrenergic receptors and arterial angiotensin-converting enzyme. The brain angiotensin system, both at the converting enzyme and at the receptor levels, is involved in cardiovascular control in the spontaneously hypertensive rat.
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