PREDICTIVE VALUE OF THE EEG IN FEBRILE SEIZURES

脑电图对热性惊厥的预测价值

• 批准号: 3968977
• 负责人: J H ELLENBERG
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3968977
• 关键词: Bosnia-Hercegovina; child (0-11); electroencephalography; febrile seizure; human subject; information systems; longitudinal human study; prognosis; relapse /recurrence

This population based study will evaluate the significance of the EEG as a predictor for recurrence of seizures in those children who have had a simple febrile convulsion. Outcome with respect to febrile seizure recurrence and afebrile seizure occurrence will be reported. The evolution of the EEG pattern will be described, and patterns will be correlated with the clinical outcome. The clinical study is being carried out in Skopje, Yugoslavia, at the Pediatric Clinic of the University of Skopje. The study began in FY '82 and will be completed in FY '88. Patient accrual was completed in December, 1984, by which time approximately 400 patients with a febrile seizure, no prior complex or multiple seizures and with a normal or nonspecific abnormal EEG, were registered into the study and began the study protocol and follow-up. An additional 200 patients with a specific abnormal EEG were entered for baseline information and follow-up. Data monitoring, editing and file creation are continuing. Statistical analysis of short-term outcomes and EEG changes will begin in FY '87. Follow-up should be completed on all patients by FY '88.

这项以人群为基础的研究将评估EEG作为一种 癫痫发作复发的预测因子 单纯性热性惊厥。与热性惊厥有关的结果 复发和无热性惊厥的发生将被报告。演变过程 将描述EEG模式的特征，并且模式将与 临床结果。这项临床研究正在斯科普里进行， 南斯拉夫，斯科普里大学儿科诊所。 这项研究始于82财年，将于88财年完成。 于1984年12月完成，到那时大约有400名患者 有发热发作，既往无复杂或多次发作，且有 正常或非特异性异常脑电登记到研究中并 开始研究方案和随访。另有200名患者患有 输入特定的异常脑电图作为基线信息和随访。 数据监测、编辑和文件创建仍在继续。统计 对短期结果和脑电变化的分析将从87财年开始。 所有患者的随访应在2018财年前完成。