ETIOLOGY AND NATURAL HISTORY OF CONVULSIVE DIOSRDERS AND CEREBRAL PALSY

惊厥性疾病和脑瘫的病因和自然史

• 批准号: 4696815
• 负责人: J H ELLENBERG
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/4696815
• 关键词: cerebral palsy; convulsions; data collection; infant human (0-1 year); information systems; longitudinal human study; nervous system disorder epidemiology; perinatal; preschool child (1-5); statistics /biometry

This study examines the relationship between perinatal and early postnatal factors and the occurrence of seizure disorders and cerebral palsy in childhood. The project derives from the data of the Collaborative Perinatal Project, a large prospectively-followed population (approixmatley 60,000 mothers, with their children followed to seven years of age). The univariate screen of material, obstetric and pediatric risk factors, demographic analyses and studies of natural history have been completed. The major focus this fiscal year has been on the multivariate assessment of the data bank which as been substantially completed, including correlation and regression analyses relating to the etiology of both disorders. Final manuscripts in each area are in progress, including pre and postnatal predictors of both disorders.

本研究探讨围产期和产后早期的关系， 脑性瘫痪的发病因素和发病率 童年. 该项目源于合作的数据 围产期项目，一个大的前瞻性随访人群（approixmatley 60，000名母亲及其子女被跟踪到7岁）。 的 材料、产科和儿科风险因素的单变量筛选， 人口分析和自然史研究已经完成。 本财政年度的主要重点是对以下方面的多变量评估： 已基本完成的数据库，包括相关性 以及与这两种疾病的病因相关的回归分析。 最终 每个领域的手稿正在编写中，包括产前和产后 这两种疾病的预测因子。