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STUDIES OF THE IMMUNOLOGIC RESPONSES TO NON-FILARIAL HELMINTH INFECTIONS

STUDIES OF THE IMMUNOLOGIC RESPONSES TO NON-FILARIAL HELMINTH INFECTIONS
非丝虫蠕虫感染的免疫反应研究
批准号：
4688420
负责人：
E A OTTESEN
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/4688420
关键词：
T lymphocyte basophils blocking antibody granuloma helminthic antigen helper T lymphocyte host organism interaction human subject immunoglobulin E immunoglobulin G immunosuppression microorganism immunology monocyte schistosomiasis suppressor T lymphocyte

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中文摘要
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英文摘要
Experimental hookworm (Necator americanus) infections in normal volunteers have been established with a goal toward defining progressive changes in immunologic responses (especially IgE) to helminth infection. An infecting dose of 50 filariform larvae was sufficient to stimulate vigorous eosinophil and moderate IgG and IgE antibody responses but was insufficient to induce strong or consistent lymphocyte blastogenic responses. Changes in eosinophil functional responsiveness were also noted.
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CLINICAL AND THERAPEUTIC STUDIES IN HUMAN FILARIASIS
STUDIES OF THE IMMUNOLOGIC RESPONSES TO NON-FILARIAL HELMINTH INFECTIONS
STUDIES OF THE IMMUNOLOGIC RESPONSES TO NON-FILARIAL HELMINTH INFECTIONS
STUDIES OF THE IMMUNOLOGIC RESPONSES TO FILARIAL INFECTIONS
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