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ANALYSIS OF BIOMEDICAL TIME SERIES DATA

ANALYSIS OF BIOMEDICAL TIME SERIES DATA
生物医学时间序列数据分析
批准号：
4693811
负责人：
H J HOFFMAN
金额：
$0.0万
依托单位：
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/4693811
关键词：
adolescence (12-20) blood chemistry child physical development circadian rhythms estradiol estriol estrone female follicle stimulating hormone human puberty human subject longitudinal human study luteinizing hormone male male castration middle childhood (6-11) pituitary gonadal axis precocious puberty radioimmunoassay somatotropin statistics /biometry urinalysis

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中文摘要
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英文摘要
The objectives of this project are: (1) to characterize developmental patterns from daily measurements of gonadotropins and for estrogens in premenarchial girls and pubescent boys based on radioimmunoassay methods for measuring urinary luteinizing hormone, urinary follicle stimulating hormone, and urinary estradiol, estriol and estrone hormones; (2) gonadotropins in both castrated and intact male monkeys of different ages; (3) growth hormone in normal and precocious pubertal children; (4) to assess circadian and other rhythms in heart rate, temperature and other serial data collected from long-term studies in humans; and (5) to perform analysis of these serial measurements using methods of statistical time series analysis, including autoregressive filtering, auto- and cross-spectrum analysis, and robust smoothing procedures.
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