Determinants of Health in Adolescence of Extremely Low Birth Weight or Extreme Prematurity

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We will uniquely determine the health outcomes at age 16 years of 298 very tiny (birth weight <1000 g) or preterm (<28 weeks' gestational age) children born in Victoria in 1991-92, compared with 262 normal birthweight children. We will track the pathways to the various health outcomes from a combination of social, biological, genetic and environmental influences, some of which have been obtained from detailed assessments of the children earlier in life, at birth, 2, 5, and 8 years of age.