ZINC DEFICIENCY IN S. MYSTAX AND ITS RELATIONSHIP TO WASTING MARMOSET SYNDROME

S. MYSTAX 缺锌及其与消瘦狨猴综合征的关系

• 批准号: 4705581
• 负责人: D E BARNARD
• 金额: --
• 依托单位: DIVISION OF RESEARCH SERVICES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/4705581
• 关键词: blood chemistry; dietary trace element; nutrient bioavailability; nutrition disorders; nutrition related tag; zinc

The purpose of this study was to determine if the etiology of Wasting Marmoset Syndrome (WMS) is related to zinc deficiency. The clinical symptoms of zinc deficiency and WMS are very similar. It was determined that S. mystax exhibiting signs of WMS were zinc deficient. The study involved feeding two diets to several wasting S. mystax, one diet was supplemented with zinc carbonate and the other was not. Serum zinc concentrations and blood chemistries were sampled on a regular basis. Tissue were taken from dead tamarins for zinc analysis. The S. mystax is an invaluable laboratory animal model for immunological research. However, in captivity, many of these tamarins are unable to breed and eventually die due to WMS. The fact that S. mystax are zinc deficient may provide an answer to the etiology of WMS. It was found dietary zinc had no effect on WMS and the data have been incorporated into another paper.

这项研究的目的是确定是否病因消瘦 绒猴综合征（WMS）与缺锌有关。 临床 锌缺乏和WMS的症状非常相似。 认定 那辆多显示WMS迹象的mystax是缺锌的。 研究 用两种饲料喂养几只消瘦的S. mystax，一种饮食是 另一个没有。 血清锌 定期对浓度和血液化学进行取样。 从死亡的绢毛猴中取出组织进行锌分析。 色葡萄Mystax是免疫学研究的宝贵实验动物模型， research. 然而，在圈养条件下，许多绢毛猴无法 繁殖并最终死于WMS。 S.牡蛎是锌的 缺乏可能提供一个答案的病因学WMS。 结果发现，日粮锌对WMS没有影响， 在另一张纸上。